The prognosis of hyponatremia at hospital admission

William M. Tierney, Douglas K. Martin, M. Carol Greenlee, Robert L. Zerbe, Clement J. McDonald

Research output: Contribution to journalArticle

93 Citations (Scopus)

Abstract

To assess the risk of mortality in patients with hyponatremia at the time of hospital admission, the authors studied data for 13,979 patients admitted over a 46-month period. Of the 763 (4%) admitted with hyponatremia, 757 (99%) were matched by age, gender, and admitting date with normonatremic control patients. Hyponatremic patients were more than seven times as likely to die in the hospital than the control patients, and they were more than twice as likely to die after discharge (p<0.0001 for both). This relationship with in- and outpatient mortality held when controlling for the diagnoses found more often in the hyponatremic patients. Hyponatremia appears to be an indicator of increased risk of death regardless of the disease with which it is associated.

Original languageEnglish (US)
Pages (from-to)380-385
Number of pages6
JournalJournal of general internal medicine
Volume1
Issue number6
DOIs
StatePublished - Nov 1 1986

Fingerprint

Hyponatremia
Mortality
Inpatients
Outpatients

Keywords

  • clinical epidemiology
  • hyponatremia
  • mortality

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Tierney, W. M., Martin, D. K., Greenlee, M. C., Zerbe, R. L., & McDonald, C. J. (1986). The prognosis of hyponatremia at hospital admission. Journal of general internal medicine, 1(6), 380-385. https://doi.org/10.1007/BF02596422

The prognosis of hyponatremia at hospital admission. / Tierney, William M.; Martin, Douglas K.; Greenlee, M. Carol; Zerbe, Robert L.; McDonald, Clement J.

In: Journal of general internal medicine, Vol. 1, No. 6, 01.11.1986, p. 380-385.

Research output: Contribution to journalArticle

Tierney, WM, Martin, DK, Greenlee, MC, Zerbe, RL & McDonald, CJ 1986, 'The prognosis of hyponatremia at hospital admission', Journal of general internal medicine, vol. 1, no. 6, pp. 380-385. https://doi.org/10.1007/BF02596422
Tierney, William M. ; Martin, Douglas K. ; Greenlee, M. Carol ; Zerbe, Robert L. ; McDonald, Clement J. / The prognosis of hyponatremia at hospital admission. In: Journal of general internal medicine. 1986 ; Vol. 1, No. 6. pp. 380-385.
@article{6329206392664ee4ad23b3f9a1bfa2c9,
title = "The prognosis of hyponatremia at hospital admission",
abstract = "To assess the risk of mortality in patients with hyponatremia at the time of hospital admission, the authors studied data for 13,979 patients admitted over a 46-month period. Of the 763 (4{\%}) admitted with hyponatremia, 757 (99{\%}) were matched by age, gender, and admitting date with normonatremic control patients. Hyponatremic patients were more than seven times as likely to die in the hospital than the control patients, and they were more than twice as likely to die after discharge (p<0.0001 for both). This relationship with in- and outpatient mortality held when controlling for the diagnoses found more often in the hyponatremic patients. Hyponatremia appears to be an indicator of increased risk of death regardless of the disease with which it is associated.",
keywords = "clinical epidemiology, hyponatremia, mortality",
author = "Tierney, {William M.} and Martin, {Douglas K.} and Greenlee, {M. Carol} and Zerbe, {Robert L.} and McDonald, {Clement J.}",
year = "1986",
month = "11",
day = "1",
doi = "10.1007/BF02596422",
language = "English (US)",
volume = "1",
pages = "380--385",
journal = "Journal of General Internal Medicine",
issn = "0884-8734",
publisher = "Springer New York",
number = "6",

}

TY - JOUR

T1 - The prognosis of hyponatremia at hospital admission

AU - Tierney, William M.

AU - Martin, Douglas K.

AU - Greenlee, M. Carol

AU - Zerbe, Robert L.

AU - McDonald, Clement J.

PY - 1986/11/1

Y1 - 1986/11/1

N2 - To assess the risk of mortality in patients with hyponatremia at the time of hospital admission, the authors studied data for 13,979 patients admitted over a 46-month period. Of the 763 (4%) admitted with hyponatremia, 757 (99%) were matched by age, gender, and admitting date with normonatremic control patients. Hyponatremic patients were more than seven times as likely to die in the hospital than the control patients, and they were more than twice as likely to die after discharge (p<0.0001 for both). This relationship with in- and outpatient mortality held when controlling for the diagnoses found more often in the hyponatremic patients. Hyponatremia appears to be an indicator of increased risk of death regardless of the disease with which it is associated.

AB - To assess the risk of mortality in patients with hyponatremia at the time of hospital admission, the authors studied data for 13,979 patients admitted over a 46-month period. Of the 763 (4%) admitted with hyponatremia, 757 (99%) were matched by age, gender, and admitting date with normonatremic control patients. Hyponatremic patients were more than seven times as likely to die in the hospital than the control patients, and they were more than twice as likely to die after discharge (p<0.0001 for both). This relationship with in- and outpatient mortality held when controlling for the diagnoses found more often in the hyponatremic patients. Hyponatremia appears to be an indicator of increased risk of death regardless of the disease with which it is associated.

KW - clinical epidemiology

KW - hyponatremia

KW - mortality

UR - http://www.scopus.com/inward/record.url?scp=0022964788&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022964788&partnerID=8YFLogxK

U2 - 10.1007/BF02596422

DO - 10.1007/BF02596422

M3 - Article

C2 - 3794837

AN - SCOPUS:0022964788

VL - 1

SP - 380

EP - 385

JO - Journal of General Internal Medicine

JF - Journal of General Internal Medicine

SN - 0884-8734

IS - 6

ER -