The representation of biological classes in the human brain

Andrew C. Connolly, J. Swaroop Guntupalli, Jason Gors, Michael Hanke, Yaroslav O. Halchenko, Yu-Chien Wu, Hervé Abdi, James V. Haxby

Research output: Contribution to journalArticle

154 Citations (Scopus)

Abstract

Evidence of category specificity from neuroimaging in the human visual system is generally limited to a few relatively coarse categorical distinctions- e.g., faces versus bodies, or animals versus artifacts-leaving unknown the neural underpinnings of fine-grained category structure within these large domains. Here we use fMRI to explore brain activity for a set of categories within the animate domain, including six animal species-two each from three very different biological classes: primates, birds, and insects. Patterns of activity throughout ventral object vision cortex reflected the biological classes of the stimuli. Specifically, the abstract representational space- measured as dissimilarity matrices defined between species-specific multivariate patterns of brain activity- correlated strongly with behavioral judgments of biological similarity of the same stimuli. This biological class structure was uncorrelated with structure measured in retinotopic visual cortex, which correlated instead with a dissimilarity matrix defined by a model of V1 cortex for the same stimuli. Additionally, analysis of the shape of the similarity space in ventral regions provides evidence for a continuum in the abstract representational space-with primates at one end and insects at the other. Further investigation into the cortical topography of activity that contributes to this category structure reveals the partial engagement of brain systems active normally for inanimate objects in addition to animate regions.

Original languageEnglish (US)
Pages (from-to)2608-2618
Number of pages11
JournalJournal of Neuroscience
Volume32
Issue number8
DOIs
StatePublished - Feb 22 2012
Externally publishedYes

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Primates
Insects
Brain
Visual Cortex
Neuroimaging
Artifacts
Birds
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Connolly, A. C., Swaroop Guntupalli, J., Gors, J., Hanke, M., Halchenko, Y. O., Wu, Y-C., ... Haxby, J. V. (2012). The representation of biological classes in the human brain. Journal of Neuroscience, 32(8), 2608-2618. https://doi.org/10.1523/JNEUROSCI.5547-11.2012

The representation of biological classes in the human brain. / Connolly, Andrew C.; Swaroop Guntupalli, J.; Gors, Jason; Hanke, Michael; Halchenko, Yaroslav O.; Wu, Yu-Chien; Abdi, Hervé; Haxby, James V.

In: Journal of Neuroscience, Vol. 32, No. 8, 22.02.2012, p. 2608-2618.

Research output: Contribution to journalArticle

Connolly, AC, Swaroop Guntupalli, J, Gors, J, Hanke, M, Halchenko, YO, Wu, Y-C, Abdi, H & Haxby, JV 2012, 'The representation of biological classes in the human brain', Journal of Neuroscience, vol. 32, no. 8, pp. 2608-2618. https://doi.org/10.1523/JNEUROSCI.5547-11.2012
Connolly AC, Swaroop Guntupalli J, Gors J, Hanke M, Halchenko YO, Wu Y-C et al. The representation of biological classes in the human brain. Journal of Neuroscience. 2012 Feb 22;32(8):2608-2618. https://doi.org/10.1523/JNEUROSCI.5547-11.2012
Connolly, Andrew C. ; Swaroop Guntupalli, J. ; Gors, Jason ; Hanke, Michael ; Halchenko, Yaroslav O. ; Wu, Yu-Chien ; Abdi, Hervé ; Haxby, James V. / The representation of biological classes in the human brain. In: Journal of Neuroscience. 2012 ; Vol. 32, No. 8. pp. 2608-2618.
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