The role of TNF-α in renal tubular cell damage following exposure to pathological conditions in vitro

Kirstan K. Meldrum, Karen Hile, Martin Kaefer, Karen M. Haberstroh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The role of TNF-α in renal tubular cell damage following exposure to pathological conditions in vitro was discussed. It was found that N-Acetyl-β-D-glucosaminidase (NAG) levels expressed by LLC-PK1 cells were decreased following exposure to hydrostatic pressure. It was suggested that decrease in the NAG levels was due to increased pressure and/or anoxia which resulted in cellular apoptosis of LLC-PK1 cells.

Original languageEnglish
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
EditorsR.D. Kamm, G.W. Schmid-Schoenbein, G.A. Atesian, M.S. Hefzy
Pages611-612
Number of pages2
Volume50
StatePublished - 2001
EventProceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States
Duration: Jun 27 2001Jul 1 2001

Other

OtherProceedings of the 2001 Bioengineering Conference
CountryUnited States
CitySnowbird, UT
Period6/27/017/1/01

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Meldrum, K. K., Hile, K., Kaefer, M., & Haberstroh, K. M. (2001). The role of TNF-α in renal tubular cell damage following exposure to pathological conditions in vitro. In R. D. Kamm, G. W. Schmid-Schoenbein, G. A. Atesian, & M. S. Hefzy (Eds.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 50, pp. 611-612)