The Sequential Organ Failure Assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation

Alan E. Jones, Stephen Trzeciak, Jeffrey A. Kline

Research output: Contribution to journalArticle

Abstract

Objectives: Organ failure worsens outcome in sepsis. The Sequential Organ Failure Assessment (SOFA) score numerically quantifies the number and severity of failed organs. We examined the utility of the SOFA score for assessing outcome of patients with severe sepsis with evidence of hypoperfusion at the time of emergency department (ED) presentation. Design: Prospective observational study. Setting: Urban, tertiary ED with an annual census of >110,000. Patients: ED patients with severe sepsis with evidence of hypoperfusion. Inclusion criteria: suspected infection, two or more criteria of systemic inflammation, and either systolic blood pressure 4 mmol/L. Exclusion criteria: age

Original languageEnglish (US)
Pages (from-to)1649-1654
Number of pages6
JournalCritical Care Medicine
Volume37
Issue number5
DOIs
StatePublished - May 2009
Externally publishedYes

Fingerprint

Organ Dysfunction Scores
Hospital Emergency Service
Sepsis
Blood Pressure
Censuses
Observational Studies
Prospective Studies
Inflammation
Infection

Keywords

  • Mortality
  • Scoring system
  • Sepsis
  • Sequential Organ Failure Assessment
  • Severe sepsis

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

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AB - Objectives: Organ failure worsens outcome in sepsis. The Sequential Organ Failure Assessment (SOFA) score numerically quantifies the number and severity of failed organs. We examined the utility of the SOFA score for assessing outcome of patients with severe sepsis with evidence of hypoperfusion at the time of emergency department (ED) presentation. Design: Prospective observational study. Setting: Urban, tertiary ED with an annual census of >110,000. Patients: ED patients with severe sepsis with evidence of hypoperfusion. Inclusion criteria: suspected infection, two or more criteria of systemic inflammation, and either systolic blood pressure 4 mmol/L. Exclusion criteria: age

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