The star-allele nomenclature

Retooling for translational genomics

J. D. Robarge, L. Li, Zeruesenay Desta, A. Nguyen, D. A. Flockhart

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The star-allele nomenclature is the result of efforts to standardize genetic polymorphism annotation for the cytochrome P450 genes. As clinical pharmacogenetic testing becomes widespread, it is important that this system effectively communicate a patient's genotype and predicted clinical phenotype. As genomics research expands, it is equally important that the system remain a valuable tool for the wider community of genetic researchers to exploit our ever-improving ability to catalog variability in the human genome.

Original languageEnglish
Pages (from-to)244-248
Number of pages5
JournalClinical Pharmacology and Therapeutics
Volume82
Issue number3
DOIs
StatePublished - Sep 2007

Fingerprint

Genetic Polymorphisms
Human Genome
Genomics
Terminology
Cytochrome P-450 Enzyme System
Alleles
Genotype
Research Personnel
Phenotype
Research
Genes
Pharmacogenomic Testing

ASJC Scopus subject areas

  • Pharmacology

Cite this

The star-allele nomenclature : Retooling for translational genomics. / Robarge, J. D.; Li, L.; Desta, Zeruesenay; Nguyen, A.; Flockhart, D. A.

In: Clinical Pharmacology and Therapeutics, Vol. 82, No. 3, 09.2007, p. 244-248.

Research output: Contribution to journalArticle

Robarge, J. D. ; Li, L. ; Desta, Zeruesenay ; Nguyen, A. ; Flockhart, D. A. / The star-allele nomenclature : Retooling for translational genomics. In: Clinical Pharmacology and Therapeutics. 2007 ; Vol. 82, No. 3. pp. 244-248.
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