The symphony of the ninth: The development and function of Th9 cells

Rukhsana Jabeen, Mark H. Kaplan

Research output: Contribution to journalReview article

72 Scopus citations

Abstract

CD4+ T helper cells are obligate regulators of inflammatory disease. An expanding cadre of T helper (Th) subsets, specialized for promoting particular types of inflammation, function through the secretion of a restricted set of cytokines. The latest addition to the list of subsets is the Th9 cell that secretes IL-9 as a signature cytokine and contributes to several classes of inflammatory disease. In this review we focus on recent advances in understanding the development of Th9 cells, and how Th9 cells contribute to the orchestration of disease.

Original languageEnglish (US)
Pages (from-to)303-307
Number of pages5
JournalCurrent Opinion in Immunology
Volume24
Issue number3
DOIs
StatePublished - Jun 1 2012

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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