The use of granulocyte colony-stimulating factor in the treatment of fever and neutropenia in a heart transplant patient

M. S. Gordon, Jacqueline O'Donnell, E. R. Mohler, M. A. Cooper

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We had the opportunity to study the clinical effects of granulocyte colony-stimulating factor in a heart transplant patient with a classic febrile neutropenic episode that was thought to be caused by immunosuppressive therapy. Administration of granulocyte colony-stimulating factor resulted in rapid recovery of his absolute neutrophil count, with resolution of fevers. Endomyocardial biopsy showed no pathologic evidence of worsened rejection. The use of hematopoietic cytokines after the organ allograft requires further study before it can be routinely advocated in this patient population.

Original languageEnglish (US)
Pages (from-to)706-707
Number of pages2
JournalJournal of Heart and Lung Transplantation
Volume12
Issue number4
StatePublished - 1993
Externally publishedYes

Fingerprint

Granulocyte Colony-Stimulating Factor
Neutropenia
Fever
Transplants
Immunosuppressive Agents
Allografts
Neutrophils
Cytokines
Biopsy
Therapeutics
Population
Clinical Studies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Transplantation

Cite this

The use of granulocyte colony-stimulating factor in the treatment of fever and neutropenia in a heart transplant patient. / Gordon, M. S.; O'Donnell, Jacqueline; Mohler, E. R.; Cooper, M. A.

In: Journal of Heart and Lung Transplantation, Vol. 12, No. 4, 1993, p. 706-707.

Research output: Contribution to journalArticle

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