Thymoma and Thymic Carcinoma

Research output: Chapter in Book/Report/Conference proceedingChapter


The thymus is an enigmatic structure located in the anterior mediastinum, whose function is to facilitate the differentiation and maturation of T lymphocytes. As such, the thymus requires a complex microenvironment and is composed of specialized epithelial cells. Thus, the thymus gland serves an integral role in the immune process and alteration of its controlled function has been associated with a protean array of disease manifestations. Thymic epithelial tumors are rare and the National Cancer Institute's Surveillance, Epidemiology and End Results tumor registry estimates the incidence of thymoma in the United States to be approximately 0.15 per 100,000 person-years.

Original languageEnglish (US)
Title of host publicationTextbook of Uncommon Cancer
PublisherJohn Wiley and Sons
Number of pages23
ISBN (Print)9781118083734
StatePublished - Sep 20 2012


  • Chemotherapy
  • Epidemiology
  • Locally invasive disease
  • Noninvasive disease
  • Nonneoplastic thymus
  • Paraneoplastic syndromes
  • Prognosis
  • Staging system
  • Thymic carcinoma
  • Thymomas

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Loehrer, P. J., Wick, M. R., & Badve, S. (2012). Thymoma and Thymic Carcinoma. In Textbook of Uncommon Cancer (pp. 279-301). John Wiley and Sons.