Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer: Possible clinical significance of large-format histology

Rodolfo Montironi, Marina Scarpelli, Andrea B. Galosi, Antonio Lopez-Beltran, Roberta Mazzucchelli, Francesco Montorsi, Liang Cheng

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Complete submission of lymphadenectomy specimens increases the number of recovered lymph nodes and the detection of metastatic disease. There are advantages with the whole-mount technique over complete sampling with standard cassettes in terms of time needed to sample the tissue, number of blocks to be cut, and slides to be examined. The clinical significance of the approach is that all lymph nodes are identified, including those that are not palpable. In particular, this approach avoids the fact that an individual lymph node is oversampled and counted according to number of pieces obtained by the pathologist, mainly in nodes with considerable size.

Original languageEnglish (US)
Pages (from-to)2059-2062
Number of pages4
JournalHuman pathology
Volume45
Issue number10
DOIs
StatePublished - Oct 1 2014

Keywords

  • Large format histology
  • Lymphadenectomy tissues
  • Prostate cancer
  • Radical prostatectomy
  • Whole-mount technique

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medicine(all)

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