Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer

Possible clinical significance of large-format histology

Rodolfo Montironi, Marina Scarpelli, Andrea B. Galosi, Antonio Lopez-Beltran, Roberta Mazzucchelli, Francesco Montorsi, Liang Cheng

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Complete submission of lymphadenectomy specimens increases the number of recovered lymph nodes and the detection of metastatic disease. There are advantages with the whole-mount technique over complete sampling with standard cassettes in terms of time needed to sample the tissue, number of blocks to be cut, and slides to be examined. The clinical significance of the approach is that all lymph nodes are identified, including those that are not palpable. In particular, this approach avoids the fact that an individual lymph node is oversampled and counted according to number of pieces obtained by the pathologist, mainly in nodes with considerable size.

Original languageEnglish
Pages (from-to)2059-2062
Number of pages4
JournalHuman Pathology
Volume45
Issue number10
DOIs
StatePublished - Oct 1 2014

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Prostatectomy
Lymph Node Excision
Prostatic Neoplasms
Histology
Lymph Nodes

Keywords

  • Large format histology
  • Lymphadenectomy tissues
  • Prostate cancer
  • Radical prostatectomy
  • Whole-mount technique

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medicine(all)

Cite this

Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer : Possible clinical significance of large-format histology. / Montironi, Rodolfo; Scarpelli, Marina; Galosi, Andrea B.; Lopez-Beltran, Antonio; Mazzucchelli, Roberta; Montorsi, Francesco; Cheng, Liang.

In: Human Pathology, Vol. 45, No. 10, 01.10.2014, p. 2059-2062.

Research output: Contribution to journalArticle

Montironi, Rodolfo ; Scarpelli, Marina ; Galosi, Andrea B. ; Lopez-Beltran, Antonio ; Mazzucchelli, Roberta ; Montorsi, Francesco ; Cheng, Liang. / Total submission of lymphadenectomy tissues removed during radical prostatectomy for prostate cancer : Possible clinical significance of large-format histology. In: Human Pathology. 2014 ; Vol. 45, No. 10. pp. 2059-2062.
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