Toxic interaction between Th2 cytokines and staphylococcus aureus in atopic dermatitis

Research output: Contribution to journalComment/debate

20 Scopus citations

Abstract

Patients with atopic dermatitis (AD) are commonly colonized/infected with Staphylococcus aureus, and this bacterium is known to worsen the dermatitis. In this issue, Brauweiler et al. demonstrate a newly discovered mechanism by which Th2 cytokines involved in AD augment the toxicity of the lytic staphylococcal protein alpha toxin. This review presents mechanisms by which Th2 cytokines may interact with S. aureus to the detriment of the dermatitis.

Original languageEnglish (US)
Pages (from-to)2069-2071
Number of pages3
JournalJournal of Investigative Dermatology
Volume134
Issue number8
DOIs
StatePublished - Aug 2014

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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