Tracheal lavage and plasma fibronectin: Relationship to respiratory distress syndrome and development of bronchopulmonary dysplasia

Jeffrey S. Gerdes, Mervin Yoder, Steven D. Douglas, Mary Paul, Mary C. Harris, Richard A. Polin

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Plasma for fibronectin determinations was obtained from 39 neonates with uncomplicated respiratory distress syndrome (RDS) and from 15 infants with RDS who developed bronchopulmonary dysplasia (BPD). Tracheal lavage fibronectin and albumin concentrations were measured in 15 infants with RDS and 15 with BPD. Control plasma fibronectin values were obtained from 20 healthy preterm infants on days 1, 2, 3, 14, and 30 of life. Control tracheal lavage fibronectin and albumin concentrations were measured in 17 neonates of various gestational ages who required tracheal intubation for nonpulmonary indications. Mean plasma fibronectin concentrations from patients with RDS was 121±11 μg/ml on days 1, 2, and 3, versus control level of 163±12 μg/ml (P

Original languageEnglish (US)
Pages (from-to)601-606
Number of pages6
JournalJournal of Pediatrics
Volume108
Issue number4
DOIs
StatePublished - 1986
Externally publishedYes

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Bronchopulmonary Dysplasia
Therapeutic Irrigation
Fibronectins
Newborn Respiratory Distress Syndrome
Albumins
Newborn Infant
Intubation
Premature Infants
Gestational Age

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Tracheal lavage and plasma fibronectin : Relationship to respiratory distress syndrome and development of bronchopulmonary dysplasia. / Gerdes, Jeffrey S.; Yoder, Mervin; Douglas, Steven D.; Paul, Mary; Harris, Mary C.; Polin, Richard A.

In: Journal of Pediatrics, Vol. 108, No. 4, 1986, p. 601-606.

Research output: Contribution to journalArticle

Gerdes, Jeffrey S. ; Yoder, Mervin ; Douglas, Steven D. ; Paul, Mary ; Harris, Mary C. ; Polin, Richard A. / Tracheal lavage and plasma fibronectin : Relationship to respiratory distress syndrome and development of bronchopulmonary dysplasia. In: Journal of Pediatrics. 1986 ; Vol. 108, No. 4. pp. 601-606.
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