trans Activation by the bovine papillomavirus E2 protein in Saccharomyces cerevisiae

L. C. Morrissey, J. Barsoum, E. J. Androphy

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

The papillomavirus E2 protein functions as an enhancer-binding factor to promote transcription in mammalian cells. We found that one copy of the E2 binding site acted as an E2 protein-dependent upstream activating sequence in Saccharomyces cerevisiae. Additional copies of the binding motif further augmented transcription. These results imply that the E2 protein functionally interacts with highly conserved transcriptional elements.

Original languageEnglish (US)
Pages (from-to)4422-4425
Number of pages4
JournalJournal of virology
Volume63
Issue number10
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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