Transfer RNA and aminoacyl transfer RNA in developing rats

D. K. Liu, E. E. McKee, P. J. Fritz

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

The total transfer RNA (tRNA) level in the liver, kidney, skeletal muscle and heart muscle of developing rats was determined by purification using (3H)tRNA as an internal standard. Liver and kidney contained almost twice as much tRNA per gram tissue as heart and skeletal muscle. There were no apparent differences between the sexes. The aminoacylation capacities of 6 tRNA species (alanyl, aspartyl, leucyl, methionyl, phenylalanyl, and tryptophanyl) from rat liver were not different during 3 developmental stages (suckling, weanling and young adult), and there were also no differences noted between males and females. The in vivo percent aminoacylation of four tRNAs (aspartyl, leucyl, methionyl, and phenylalanyl) was lower during the newborn and suckling periods than in weanling and young adult rat livers. The tRNA of young adults was almost completely aminoacylated in vivo with the exception of alanyl tRNA.

Original languageEnglish (US)
Title of host publicationBiology of the Neonate - Foetal and Neonatal Research
Pages27-35
Number of pages9
Volume28
Edition1-2
StatePublished - 1976
Externally publishedYes

Fingerprint

Transfer RNA
Young Adult
Liver
Myocardium
Skeletal Muscle
Transfer RNA Aminoacylation
Aminoacylation
Kidney
Sex Characteristics
Newborn Infant

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Cite this

Liu, D. K., McKee, E. E., & Fritz, P. J. (1976). Transfer RNA and aminoacyl transfer RNA in developing rats. In Biology of the Neonate - Foetal and Neonatal Research (1-2 ed., Vol. 28, pp. 27-35)

Transfer RNA and aminoacyl transfer RNA in developing rats. / Liu, D. K.; McKee, E. E.; Fritz, P. J.

Biology of the Neonate - Foetal and Neonatal Research. Vol. 28 1-2. ed. 1976. p. 27-35.

Research output: Chapter in Book/Report/Conference proceedingChapter

Liu, DK, McKee, EE & Fritz, PJ 1976, Transfer RNA and aminoacyl transfer RNA in developing rats. in Biology of the Neonate - Foetal and Neonatal Research. 1-2 edn, vol. 28, pp. 27-35.
Liu DK, McKee EE, Fritz PJ. Transfer RNA and aminoacyl transfer RNA in developing rats. In Biology of the Neonate - Foetal and Neonatal Research. 1-2 ed. Vol. 28. 1976. p. 27-35
Liu, D. K. ; McKee, E. E. ; Fritz, P. J. / Transfer RNA and aminoacyl transfer RNA in developing rats. Biology of the Neonate - Foetal and Neonatal Research. Vol. 28 1-2. ed. 1976. pp. 27-35
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