Transjugular intrahepatic portosystemic shunting (TIPS) for treatment of severe hepatic veno-occlusive disease

F. O. Smith, M. S. Johnson, L. R. Scherer, P. Faught, P. P. Breitfeld, E. Albright, S. C. Hillier, D. Gowan, P. D. Smith, Kent Robertson, D. Emanuel

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Severe veno-occlusive disease (VOD) of the liver is a frequent cause of morbidity and mortality in patients undergoing transplantation. While surgical portosystemic shunts have been reported to be useful in the treatment of severe hepatic VOD with intractable ascites, few of these patients are surgical candidates. We report a case of severe VOD after autologous peripheral blood progenitor cell transplantation treated with transjugular intrahepatic portosystemic shunting (TIPS). This procedure resulted in marked improvement in the patient's ascites, coagulation status and urinary output. The safety and efficacy of this non-surgical approach for the treatment of patients with severe VOD requires prospective studies.

Original languageEnglish
Pages (from-to)643-646
Number of pages4
JournalBone Marrow Transplantation
Volume18
Issue number3
StatePublished - Sep 1996

Fingerprint

Hepatic Veno-Occlusive Disease
Ascites
Surgical Portasystemic Shunt
Cell Transplantation
Therapeutics
Liver Diseases
Blood Cells
Stem Cells
Transplantation
Prospective Studies
Morbidity
Safety
Mortality

Keywords

  • Bone marrow transplantation
  • Transjugular intra hepatic portosystemic shunting (TIPS)
  • Veno-occlusive disease

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Smith, F. O., Johnson, M. S., Scherer, L. R., Faught, P., Breitfeld, P. P., Albright, E., ... Emanuel, D. (1996). Transjugular intrahepatic portosystemic shunting (TIPS) for treatment of severe hepatic veno-occlusive disease. Bone Marrow Transplantation, 18(3), 643-646.

Transjugular intrahepatic portosystemic shunting (TIPS) for treatment of severe hepatic veno-occlusive disease. / Smith, F. O.; Johnson, M. S.; Scherer, L. R.; Faught, P.; Breitfeld, P. P.; Albright, E.; Hillier, S. C.; Gowan, D.; Smith, P. D.; Robertson, Kent; Emanuel, D.

In: Bone Marrow Transplantation, Vol. 18, No. 3, 09.1996, p. 643-646.

Research output: Contribution to journalArticle

Smith, FO, Johnson, MS, Scherer, LR, Faught, P, Breitfeld, PP, Albright, E, Hillier, SC, Gowan, D, Smith, PD, Robertson, K & Emanuel, D 1996, 'Transjugular intrahepatic portosystemic shunting (TIPS) for treatment of severe hepatic veno-occlusive disease', Bone Marrow Transplantation, vol. 18, no. 3, pp. 643-646.
Smith FO, Johnson MS, Scherer LR, Faught P, Breitfeld PP, Albright E et al. Transjugular intrahepatic portosystemic shunting (TIPS) for treatment of severe hepatic veno-occlusive disease. Bone Marrow Transplantation. 1996 Sep;18(3):643-646.
Smith, F. O. ; Johnson, M. S. ; Scherer, L. R. ; Faught, P. ; Breitfeld, P. P. ; Albright, E. ; Hillier, S. C. ; Gowan, D. ; Smith, P. D. ; Robertson, Kent ; Emanuel, D. / Transjugular intrahepatic portosystemic shunting (TIPS) for treatment of severe hepatic veno-occlusive disease. In: Bone Marrow Transplantation. 1996 ; Vol. 18, No. 3. pp. 643-646.
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