Translational systems pharmacology studies in pregnant women

Sara Quinney, Rakesh Gullapelli, David Haas

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Pregnancy involves rapid physiological adaptation and complex interplay between mother and fetus. New analytic technologies provide large amounts of genomic, proteomic, and metabolomics data. The integration of these data through bioinformatics, statistical, and systems pharmacology techniques can improve our understanding of the mechanisms of normal maternal physiologic changes and fetal development. New insights into the mechanisms of pregnancy-related disorders, such as preterm birth (PTB), may lead to the development of new therapeutic interventions and novel biomarkers.

Original languageEnglish (US)
JournalCPT: Pharmacometrics and Systems Pharmacology
DOIs
StateAccepted/In press - Jan 1 2017

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Pharmacology
Pregnancy
Biomarkers
Bioinformatics
Pregnant Women
Mothers
Physiological Adaptation
Metabolomics
Proteomics
Premature Birth
Fetal Development
Computational Biology
Genomics
Disorder
Fetus
Technology
Therapeutics

ASJC Scopus subject areas

  • Modeling and Simulation
  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

Cite this

Translational systems pharmacology studies in pregnant women. / Quinney, Sara; Gullapelli, Rakesh; Haas, David.

In: CPT: Pharmacometrics and Systems Pharmacology, 01.01.2017.

Research output: Contribution to journalArticle

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