Trends in Outcomes, Financial Burden, and Mortality for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) in the United States from 2002 to 2010

Chetna Jinjuvadia, Raxitkumar Jinjuvadia, Chaitanya Mandapakala, Navin Durairajan, Suthat Liangpunsakul, Ayman O. Soubani

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Chronic obstructive pulmonary disease (COPD) is the cause of substantial economic and social burden. We evaluated the temporal trends of hospitalizations from acute exacerbation of COPD and determined its outcome and financial impact using the National (Nationwide) Inpatient Sample (NIS) databases (2002–2010). Individuals aged ≥ 18 years were included. Subjects who were hospitalized with primary diagnosis of COPD exacerbation and those who were admitted for other causes but had underlying acute exacerbation of COPD (secondary diagnosis) were captured by International Classification of Diseases-Ninth Revision (ICD-9) codes. The hospital outcomes and length of stay were determined. Multivariate logistic regression was used to identify the independent predictors of inpatient mortality. Overall acute exacerbation of COPD-related hospitalizations accounted for nearly 3.31% of all hospitalizations in the year 2002. This did not change significantly to year 2010 (3.43%, p = 0.608). However, there was an increase in hospitalization with secondary diagnosis of COPD. Elderly white patients accounted for most of the hospitalizations. Medicare was the primary payer source for most of the hospitalizations (73–75%). There was a significant decrease in inpatient mortality from 4.8% in 2002 to 3.9% in 2010 (slope –0.096, p < 0.001). Similarly, there was a significant decrease in average length of stay from 6.4 days in 2002 to 6.0 days in 2010 (slope –0.042, p < 0.001). Despite this, the hospitalization cost was increased substantially from $22,187 in 2002 to $38,455 in 2010. However, financial burden has increased over the years.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalCOPD: Journal of Chronic Obstructive Pulmonary Disease
DOIs
StateAccepted/In press - Jul 15 2016
Externally publishedYes

Fingerprint

Chronic Obstructive Pulmonary Disease
Hospitalization
Mortality
International Classification of Diseases
Inpatients
Length of Stay
Medicare
Disease Progression
Logistic Models
Economics
Databases
Costs and Cost Analysis

Keywords

  • COPD
  • hospitalization costs
  • mortality
  • NIS data

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Trends in Outcomes, Financial Burden, and Mortality for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) in the United States from 2002 to 2010. / Jinjuvadia, Chetna; Jinjuvadia, Raxitkumar; Mandapakala, Chaitanya; Durairajan, Navin; Liangpunsakul, Suthat; Soubani, Ayman O.

In: COPD: Journal of Chronic Obstructive Pulmonary Disease, 15.07.2016, p. 1-8.

Research output: Contribution to journalArticle

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