Ultrastructure and alkaline phosphatase activity of the dome epithelium of canine Peyer's patches

Harm HogenEsch, Peter J. Felsburg

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The dome epithelium of Peyer's patches from different parts of the intestine of four dogs was examined by scanning and transmission electron-microscopy and by alkaline phosphatase histochemistry on glycol-methacrylate embedded sections. M cells were scattered among more numerous enterocytes in duodenal and jejunal Peyer's patches, but constituted the major cellular component of dome epithelia of the ileal Peyer's patches. Alkaline phosphatase histochemistry demonstrated low enzyme activity in the brush border of M cells, as compared to enterocytes, in the duodenum and jejunum, allowing identification of M cells at the light microscopic level. Alkaline phosphatase activity was too low in ileal enterocytes to permit visualization of M cells. The presence of intrafollicular invaginations of dome epithelium is a consistent finding in duodenal Peyer's patches of the dog and these invaginations were characterized by few M cells, many intraepithelial lymphocytes and strong alkaline phosphatase activity.

Original languageEnglish (US)
Pages (from-to)177-186
Number of pages10
JournalVeterinary Immunology and Immunopathology
Volume24
Issue number2
DOIs
StatePublished - 1990
Externally publishedYes

Fingerprint

Peyer's Patches
Peyer's patches
Alkaline Phosphatase
alkaline phosphatase
Canidae
ultrastructure
epithelium
Epithelium
Enterocytes
enterocytes
dogs
histochemistry
cells
Dogs
glycols
Scanning Transmission Electron Microscopy
Jejunum
Microvilli
jejunum
microvilli

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Immunology
  • veterinary(all)

Cite this

Ultrastructure and alkaline phosphatase activity of the dome epithelium of canine Peyer's patches. / HogenEsch, Harm; Felsburg, Peter J.

In: Veterinary Immunology and Immunopathology, Vol. 24, No. 2, 1990, p. 177-186.

Research output: Contribution to journalArticle

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