Ultrastructure of Buschke-Loewenstein tumor

M. T. Hull, J. N. Eble, J. B. Priest, J. J. Mulcahy

Research output: Contribution to journalArticle

24 Scopus citations


A 44-year-old man suffered a Buschke-Loewenstein tumor that was treated by distal penectomy. Ultrastructurally, this tumor showed widened intercellular spaces, prominent microvilli, decreased numbers of and incompletely developed desmosomes, decreased tonofilaments, cytoplasmic dense bodies, enlarged nucleoli and annular nuclear bodies. These ultrastructural features are quite similar to those of squamous carcinoma but are dissimilar to those of condyloma acuminatum and, to a lesser extent, verrucous carcinoma. These data suggest that electron microscopy may be useful in differentiating the neoplastic Buschke-Loewenstein tumor from large condyloma acuminatum.

Original languageEnglish (US)
Pages (from-to)485-489
Number of pages5
JournalJournal of Urology
Issue number4
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Urology

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