Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma

Yawei Zhang, Theodore R. Holford, Brian Leaderer, Peter Boyle, Yong Zhu, Rong Wang, Kaiyong Zou, Bing Zhang, John Pierce Wise, Qin Qin, Briseis Kilfoy, Jiali Han, Tongzhang Zheng

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Sun exposure has been suggested to increase the risk of non-Hodgkin's lymphoma. The authors analyzed data from a population-based, case-control study of Connecticut women between 1996 and 2000 to study the hypothesis. Women who reported having had a suntan experienced an increased risk of non-Hodgkin's lymphoma with increasing duration (ptrend = 0.0062) compared with women who reported never having had a suntan. An almost threefold increased risk of non-Hodgkin's lymphoma was observed among women who reported having had a suntan for less than 3 months per year and a suntan history of more than 60 years (odds ratio = 2.8, 95% confidence interval: 1.6, 4.9) compared with those who reported never having had a suntan. For women who reported having spent time in strong sunlight between 9 a.m. and 3 p.m. during the summer, a 70% increased risk of non-Hodgkin's lymphoma was observed for the highest tertile of duration compared with the lowest (odds ratio = 1.7, 95% confidence interval: 1.2, 2.4). The risk increased with increasing duration of time spent in strong sunlight in summer (ptrend = 0.0051). The risk appears to vary by non-Hodgkin's lymphoma subtypes. Further investigations of the role of ultraviolet radiation on the risk of non-Hodgkin's lymphoma are warranted.

Original languageEnglish (US)
Pages (from-to)1255-1264
Number of pages10
JournalAmerican Journal of Epidemiology
Volume165
Issue number11
DOIs
StatePublished - Jun 1 2007
Externally publishedYes

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Suntan
Non-Hodgkin's Lymphoma
Sunlight
Odds Ratio
Confidence Intervals
Solar System
Radiation Exposure
Case-Control Studies
Radiation
Population

Keywords

  • Case-control studies
  • Lymphoma, non-Hodgkin
  • Radiation, nonionizing
  • Ultraviolet rays

ASJC Scopus subject areas

  • Epidemiology

Cite this

Zhang, Y., Holford, T. R., Leaderer, B., Boyle, P., Zhu, Y., Wang, R., ... Zheng, T. (2007). Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma. American Journal of Epidemiology, 165(11), 1255-1264. https://doi.org/10.1093/aje/kwm020

Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma. / Zhang, Yawei; Holford, Theodore R.; Leaderer, Brian; Boyle, Peter; Zhu, Yong; Wang, Rong; Zou, Kaiyong; Zhang, Bing; Wise, John Pierce; Qin, Qin; Kilfoy, Briseis; Han, Jiali; Zheng, Tongzhang.

In: American Journal of Epidemiology, Vol. 165, No. 11, 01.06.2007, p. 1255-1264.

Research output: Contribution to journalArticle

Zhang, Y, Holford, TR, Leaderer, B, Boyle, P, Zhu, Y, Wang, R, Zou, K, Zhang, B, Wise, JP, Qin, Q, Kilfoy, B, Han, J & Zheng, T 2007, 'Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma', American Journal of Epidemiology, vol. 165, no. 11, pp. 1255-1264. https://doi.org/10.1093/aje/kwm020
Zhang Y, Holford TR, Leaderer B, Boyle P, Zhu Y, Wang R et al. Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma. American Journal of Epidemiology. 2007 Jun 1;165(11):1255-1264. https://doi.org/10.1093/aje/kwm020
Zhang, Yawei ; Holford, Theodore R. ; Leaderer, Brian ; Boyle, Peter ; Zhu, Yong ; Wang, Rong ; Zou, Kaiyong ; Zhang, Bing ; Wise, John Pierce ; Qin, Qin ; Kilfoy, Briseis ; Han, Jiali ; Zheng, Tongzhang. / Ultraviolet radiation exposure and risk of non-Hodgkin's lymphoma. In: American Journal of Epidemiology. 2007 ; Vol. 165, No. 11. pp. 1255-1264.
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