Undiagnosed myasthenia gravis owing to a very unusual primary presentation

Khurram A. Khan, Jeffrey D. Bennett

Research output: Contribution to journalArticle

5 Scopus citations


Myasthenia gravis (MG) is an uncommon autoimmune disorder presenting with fluctuating, progressive muscle weakness. The typical initial presentation includes ocular symptoms of ptosis, diplopia, or both. In the literature, other late symptoms have been described. The inability to close the jaws or difficulty in closing the jaws is an uncommon symptom of muscle weakness. Studies have found that only 4% of patients with MG ever complain of, or demonstrate, masticatory muscular weakness with an inability to close the jaws or difficulty in closing the jaws. In the present case, although the patient may have manifested other symptoms, his primary complaint was the inability to masticate as a result of muscular weakness and the difficulty in closing the jaw. The symptoms had reportedly been present for several months. The case is interesting in that the patient presented with an uncommon symptom as the primary complaint. The patient's recall and communication of his medical history was poor, and it is unclear as to all the factors that may have delayed the diagnosis. However, it is important for dentists to recognize these atypical symptoms of MG so that they can either order the initial tests or make the appropriate referral.

Original languageEnglish (US)
Pages (from-to)e101-e104
JournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Issue number4
StatePublished - Oct 1 2014

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Pathology and Forensic Medicine
  • Dentistry (miscellaneous)
  • Radiology Nuclear Medicine and imaging

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