Unusual presentations of lymphoma of the head and neck in childhood

Edward C. Weisberger, Darrell Davidson

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Lymphoma of the head and neck in children can pose a significant diagnostic problem, especially when histologic analysis indicates non-Hodgkin’s lymphoma and the initial site of involvement is extranodal. This report describes 15 pediatric cases of lymphoma seen from 1981 to 1987 with an initial presentation in the head and neck. Cervical lymph nodes represented the initial site of involvement in 10 of the cases. The other five cases presented with disease in the tonsillar fossa; maxillary sinus and mandible; parotid; pharyngeal wall; trachea and thyroid gland; and ethmoid sinus, sphenoid sinus, and anterior fossa. The histologic type was non-Hodgkin’s lymphoma in 12 cases and Hodgkin’s lymphoma in 3 cases. Our experience has shown that lymphoma of the head and neck in children presents a confusing clinical picture and was initially confused with inflammatory disease, polymorphic reticulosis, and other neoplasms such as rhabdomyosarcoma. In one patient, Epstein-Barr virus infection and an inherited immunodeficiency state probably played a role in the pathogenesis of the lymphoma.

Original languageEnglish
Pages (from-to)337-342
Number of pages6
JournalLaryngoscope
Volume100
Issue number4
StatePublished - 1990

Fingerprint

Lymphoma
Neck
Head
Non-Hodgkin's Lymphoma
Lethal Midline Granuloma
Ethmoid Sinus
Sphenoid Sinus
Epstein-Barr Virus Infections
Rhabdomyosarcoma
Maxillary Sinus
Trachea
Hodgkin Disease
Mandible
Thyroid Gland
Lymph Nodes
Pediatrics
Neoplasms

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Unusual presentations of lymphoma of the head and neck in childhood. / Weisberger, Edward C.; Davidson, Darrell.

In: Laryngoscope, Vol. 100, No. 4, 1990, p. 337-342.

Research output: Contribution to journalArticle

Weisberger, Edward C. ; Davidson, Darrell. / Unusual presentations of lymphoma of the head and neck in childhood. In: Laryngoscope. 1990 ; Vol. 100, No. 4. pp. 337-342.
@article{acd599568bb1460083e7b8582109317e,
title = "Unusual presentations of lymphoma of the head and neck in childhood",
abstract = "Lymphoma of the head and neck in children can pose a significant diagnostic problem, especially when histologic analysis indicates non-Hodgkin’s lymphoma and the initial site of involvement is extranodal. This report describes 15 pediatric cases of lymphoma seen from 1981 to 1987 with an initial presentation in the head and neck. Cervical lymph nodes represented the initial site of involvement in 10 of the cases. The other five cases presented with disease in the tonsillar fossa; maxillary sinus and mandible; parotid; pharyngeal wall; trachea and thyroid gland; and ethmoid sinus, sphenoid sinus, and anterior fossa. The histologic type was non-Hodgkin’s lymphoma in 12 cases and Hodgkin’s lymphoma in 3 cases. Our experience has shown that lymphoma of the head and neck in children presents a confusing clinical picture and was initially confused with inflammatory disease, polymorphic reticulosis, and other neoplasms such as rhabdomyosarcoma. In one patient, Epstein-Barr virus infection and an inherited immunodeficiency state probably played a role in the pathogenesis of the lymphoma.",
author = "Weisberger, {Edward C.} and Darrell Davidson",
year = "1990",
language = "English",
volume = "100",
pages = "337--342",
journal = "Laryngoscope",
issn = "0023-852X",
publisher = "John Wiley and Sons Inc.",
number = "4",

}

TY - JOUR

T1 - Unusual presentations of lymphoma of the head and neck in childhood

AU - Weisberger, Edward C.

AU - Davidson, Darrell

PY - 1990

Y1 - 1990

N2 - Lymphoma of the head and neck in children can pose a significant diagnostic problem, especially when histologic analysis indicates non-Hodgkin’s lymphoma and the initial site of involvement is extranodal. This report describes 15 pediatric cases of lymphoma seen from 1981 to 1987 with an initial presentation in the head and neck. Cervical lymph nodes represented the initial site of involvement in 10 of the cases. The other five cases presented with disease in the tonsillar fossa; maxillary sinus and mandible; parotid; pharyngeal wall; trachea and thyroid gland; and ethmoid sinus, sphenoid sinus, and anterior fossa. The histologic type was non-Hodgkin’s lymphoma in 12 cases and Hodgkin’s lymphoma in 3 cases. Our experience has shown that lymphoma of the head and neck in children presents a confusing clinical picture and was initially confused with inflammatory disease, polymorphic reticulosis, and other neoplasms such as rhabdomyosarcoma. In one patient, Epstein-Barr virus infection and an inherited immunodeficiency state probably played a role in the pathogenesis of the lymphoma.

AB - Lymphoma of the head and neck in children can pose a significant diagnostic problem, especially when histologic analysis indicates non-Hodgkin’s lymphoma and the initial site of involvement is extranodal. This report describes 15 pediatric cases of lymphoma seen from 1981 to 1987 with an initial presentation in the head and neck. Cervical lymph nodes represented the initial site of involvement in 10 of the cases. The other five cases presented with disease in the tonsillar fossa; maxillary sinus and mandible; parotid; pharyngeal wall; trachea and thyroid gland; and ethmoid sinus, sphenoid sinus, and anterior fossa. The histologic type was non-Hodgkin’s lymphoma in 12 cases and Hodgkin’s lymphoma in 3 cases. Our experience has shown that lymphoma of the head and neck in children presents a confusing clinical picture and was initially confused with inflammatory disease, polymorphic reticulosis, and other neoplasms such as rhabdomyosarcoma. In one patient, Epstein-Barr virus infection and an inherited immunodeficiency state probably played a role in the pathogenesis of the lymphoma.

UR - http://www.scopus.com/inward/record.url?scp=0025349583&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025349583&partnerID=8YFLogxK

M3 - Article

VL - 100

SP - 337

EP - 342

JO - Laryngoscope

JF - Laryngoscope

SN - 0023-852X

IS - 4

ER -