Abstract
The vast majority of prostatic tumors developing in adult males are adenocarcinomas. For the most part, variations in histology have not received specific designations and, from a practical approach, have had any specific prognostic implications handled through application of the Gleason grading system. Nonetheless, some of the adenocarcinoma variants have specific clinical features and differential diagnoses. Furthermore, there has been some controversy regarding the appropriate application of the Gleason grading scheme in these tumors. In addition, there are carcinomas that are in fact not adenocarcinomas and that should be kept as distinct entities. In this paper, the histologic variants of adenocarcinoma are reviewed with emphasis on clinicopathologic features and the clinical relevance of these subtypes. Other carcinomas that occur in the prostate gland are also discussed again with a focus on the clinicopathologic characteristics.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 316-327 |
| Number of pages | 12 |
| Journal | Modern Pathology |
| Volume | 17 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2004 |
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Keywords
- Adenocarcinoma
- Basaloid carcinoma
- Prostate gland
- Small-cell carcinoma
- Squamous cell carcinoma
- Urothelial carcinoma
- Variants
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Unusual subtypes of prostate cancer. / Grignon, David J.
In: Modern Pathology, Vol. 17, No. 3, 01.03.2004, p. 316-327.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Unusual subtypes of prostate cancer
AU - Grignon, David J.
PY - 2004/3/1
Y1 - 2004/3/1
N2 - The vast majority of prostatic tumors developing in adult males are adenocarcinomas. For the most part, variations in histology have not received specific designations and, from a practical approach, have had any specific prognostic implications handled through application of the Gleason grading system. Nonetheless, some of the adenocarcinoma variants have specific clinical features and differential diagnoses. Furthermore, there has been some controversy regarding the appropriate application of the Gleason grading scheme in these tumors. In addition, there are carcinomas that are in fact not adenocarcinomas and that should be kept as distinct entities. In this paper, the histologic variants of adenocarcinoma are reviewed with emphasis on clinicopathologic features and the clinical relevance of these subtypes. Other carcinomas that occur in the prostate gland are also discussed again with a focus on the clinicopathologic characteristics.
AB - The vast majority of prostatic tumors developing in adult males are adenocarcinomas. For the most part, variations in histology have not received specific designations and, from a practical approach, have had any specific prognostic implications handled through application of the Gleason grading system. Nonetheless, some of the adenocarcinoma variants have specific clinical features and differential diagnoses. Furthermore, there has been some controversy regarding the appropriate application of the Gleason grading scheme in these tumors. In addition, there are carcinomas that are in fact not adenocarcinomas and that should be kept as distinct entities. In this paper, the histologic variants of adenocarcinoma are reviewed with emphasis on clinicopathologic features and the clinical relevance of these subtypes. Other carcinomas that occur in the prostate gland are also discussed again with a focus on the clinicopathologic characteristics.
KW - Adenocarcinoma
KW - Basaloid carcinoma
KW - Prostate gland
KW - Small-cell carcinoma
KW - Squamous cell carcinoma
KW - Urothelial carcinoma
KW - Variants
UR - http://www.scopus.com/inward/record.url?scp=7444243188&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=7444243188&partnerID=8YFLogxK
U2 - 10.1038/modpathol.3800052
DO - 10.1038/modpathol.3800052
M3 - Review article
C2 - 14976541
AN - SCOPUS:7444243188
VL - 17
SP - 316
EP - 327
JO - Modern Pathology
JF - Modern Pathology
SN - 0893-3952
IS - 3
ER -