Unusual subtypes of prostate cancer

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

The vast majority of prostatic tumors developing in adult males are adenocarcinomas. For the most part, variations in histology have not received specific designations and, from a practical approach, have had any specific prognostic implications handled through application of the Gleason grading system. Nonetheless, some of the adenocarcinoma variants have specific clinical features and differential diagnoses. Furthermore, there has been some controversy regarding the appropriate application of the Gleason grading scheme in these tumors. In addition, there are carcinomas that are in fact not adenocarcinomas and that should be kept as distinct entities. In this paper, the histologic variants of adenocarcinoma are reviewed with emphasis on clinicopathologic features and the clinical relevance of these subtypes. Other carcinomas that occur in the prostate gland are also discussed again with a focus on the clinicopathologic characteristics.

Original languageEnglish (US)
Pages (from-to)316-327
Number of pages12
JournalModern Pathology
Volume17
Issue number3
DOIs
StatePublished - Mar 2004
Externally publishedYes

Fingerprint

Prostatic Neoplasms
Adenocarcinoma
Neoplasm Grading
Carcinoma
Prostate
Neoplasms
Histology
Differential Diagnosis

Keywords

  • Adenocarcinoma
  • Basaloid carcinoma
  • Prostate gland
  • Small-cell carcinoma
  • Squamous cell carcinoma
  • Urothelial carcinoma
  • Variants

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Unusual subtypes of prostate cancer. / Grignon, David.

In: Modern Pathology, Vol. 17, No. 3, 03.2004, p. 316-327.

Research output: Contribution to journalArticle

Grignon, David. / Unusual subtypes of prostate cancer. In: Modern Pathology. 2004 ; Vol. 17, No. 3. pp. 316-327.
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