Esophageal motility disorders (EMDs) represent a diverse group of conditions that alter normal peristalsis and passage of food from the esophagus into the stomach. Symptoms most commonly include dysphagia and chest pain. Differentiation from other common conditions such as coronary artery disease, gastroesophageal reflux disease and malignancy may be difficult. Standard evaluation includes upper endoscopy, barium esophagram and high-resolution esophageal manometry. The best-characterized EMD is achalasia, which causes esophageal aperistalsis and a poorly relaxing lower esophageal sphincter (LES). Treatment of achalasia focuses on reducing the pressure of the LES to allow gravity to enable passage of food into the stomach. Pneumatic dilation and laparoscopic Heller myotomy (LHM) with fundoplication are the standard treatments for achalasia. Per-oral endoscopic myotomy (POEM) represents the newest endoscopic treatment for achalasia and early data suggests efficacy comparable to that of Heller myotomy.
|Original language||English (US)|
|Pages (from-to)||15-17 and 23-24|
|State||Published - Mar 2019|
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