Updated clinical classification of pulmonary hypertension

Gerald Simonneau, Michael A. Gatzoulis, Ian Adatia, David Celermajer, Chris Denton, Ardeschir Ghofrani, Miguel Angel Gomez Sanchez, R. Krishna Kumar, Michael Landzberg, Roberto Machado, Horst Olschewski, Ivan M. Robbins, Rogiero Souza

Research output: Contribution to journalArticle

1552 Citations (Scopus)

Abstract

In 1998, a clinical classification of pulmonary hypertension (PH) was established, categorizing PH into groups which share similar pathological and hemodynamic characteristics and therapeutic approaches. During the 5th World Symposium held in Nice, France, in 2013, the consensus was reached to maintain the general scheme of previous clinical classifications. However, modifications and updates especially for Group 1 patients (pulmonary arterial hypertension [PAH]) were proposed. The main change was to withdraw persistent pulmonary hypertension of the newborn (PPHN) from Group 1 because this entity carries more differences than similarities with other PAH subgroups. In the current classification, PPHN is now designated number 1. Pulmonary hypertension associated with chronic hemolytic anemia has been moved from Group 1 PAH to Group 5, unclear/multifactorial mechanism. In addition, it was decided to add specific items related to pediatric pulmonary hypertension in order to create a comprehensive, common classification for both adults and children. Therefore, congenital or acquired left-heart inflow/outflow obstructive lesions and congenital cardiomyopathies have been added to Group 2, and segmental pulmonary hypertension has been added to Group 5. Last, there were no changes for Groups 2, 3, and 4.

Original languageEnglish (US)
JournalJournal of the American College of Cardiology
Volume62
Issue number25 SUPPL.
DOIs
StatePublished - Dec 24 2013
Externally publishedYes

Fingerprint

Pulmonary Hypertension
Persistent Fetal Circulation Syndrome
Hemolytic Anemia
Cardiomyopathies
France
Hemodynamics
Pediatrics

Keywords

  • chronic thromboembolic pulmonary hypertension
  • PH due to chronic lung diseases
  • PH due to left heart disease
  • pulmonary arterial hypertension
  • pulmonary hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Simonneau, G., Gatzoulis, M. A., Adatia, I., Celermajer, D., Denton, C., Ghofrani, A., ... Souza, R. (2013). Updated clinical classification of pulmonary hypertension. Journal of the American College of Cardiology, 62(25 SUPPL.). https://doi.org/10.1016/j.jacc.2013.10.029

Updated clinical classification of pulmonary hypertension. / Simonneau, Gerald; Gatzoulis, Michael A.; Adatia, Ian; Celermajer, David; Denton, Chris; Ghofrani, Ardeschir; Gomez Sanchez, Miguel Angel; Krishna Kumar, R.; Landzberg, Michael; Machado, Roberto; Olschewski, Horst; Robbins, Ivan M.; Souza, Rogiero.

In: Journal of the American College of Cardiology, Vol. 62, No. 25 SUPPL., 24.12.2013.

Research output: Contribution to journalArticle

Simonneau, G, Gatzoulis, MA, Adatia, I, Celermajer, D, Denton, C, Ghofrani, A, Gomez Sanchez, MA, Krishna Kumar, R, Landzberg, M, Machado, R, Olschewski, H, Robbins, IM & Souza, R 2013, 'Updated clinical classification of pulmonary hypertension', Journal of the American College of Cardiology, vol. 62, no. 25 SUPPL.. https://doi.org/10.1016/j.jacc.2013.10.029
Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A et al. Updated clinical classification of pulmonary hypertension. Journal of the American College of Cardiology. 2013 Dec 24;62(25 SUPPL.). https://doi.org/10.1016/j.jacc.2013.10.029
Simonneau, Gerald ; Gatzoulis, Michael A. ; Adatia, Ian ; Celermajer, David ; Denton, Chris ; Ghofrani, Ardeschir ; Gomez Sanchez, Miguel Angel ; Krishna Kumar, R. ; Landzberg, Michael ; Machado, Roberto ; Olschewski, Horst ; Robbins, Ivan M. ; Souza, Rogiero. / Updated clinical classification of pulmonary hypertension. In: Journal of the American College of Cardiology. 2013 ; Vol. 62, No. 25 SUPPL.
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