Uptake and transneuronal transport of horseradish peroxidase-wheat germ agglutinin by tooth pulp primary afferent neurons

Dennis F. Turner, Carl F. Marfurt

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Horseradish peroxidase-wheat germ agglutinin (HRP-WGA) applied to proximal stumps of tooth pulp primary afferent neurons in rats was taken up and transported transneuronally to neurons in the ipsilateral trigeminal brainstem nuclear complex. The results of this study suggest that HRP-WGA transport may be a novel means of labeling both primary and higher order neurons that transmit tooth pulp sensory information in the rat and may be used to investigate the fine structure and synaptic contacts of central nervous system neurons that receive tooth pulp afferent input.

Original languageEnglish (US)
Pages (from-to)381-387
Number of pages7
JournalBrain research
Volume452
Issue number1-2
DOIs
StatePublished - Jun 14 1988

Keywords

  • Horseradish peroxidase
  • Tooth pulp afferent neuron
  • Transneuronal transport
  • Wheatgerm agglutinin conjugate

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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