Urinary bladder cancer: Role of MR imaging

Sadhna Verma, Arumugam Rajesh, Srinivasa R. Prasad, Krishnanath Gaitonde, Chandana G. Lall, Vladimir Mouraviev, Gunjan Aeron, Robert B. Bracken, Kumaresan Sandrasegaran

Research output: Contribution to journalArticle

71 Scopus citations


Urinary bladder cancer is a heterogeneous disease with a variety of pathologic features, cytogenetic characteristics, and natural histories. It is the fourth most common cancer in males and the tenth most common cancer in females. Urinary bladder cancer has a high recurrence rate, necessitating long-term surveillance after initial therapy. Early detection is important, since up to 47% of bladder cancer-related deaths may have been avoided. Conventional computed tomography (CT) and magnetic resonance (MR) imaging are only moderately accurate in the diagnosis and local staging of bladder cancer, with cystoscopy and pathologic staging remaining the standards of reference. However, the role of newer MR imaging sequences (eg, diffusion-weighted imaging) in the diagnosis and local staging of bladder cancer is still evolving. Substantial advances in MR imaging technology have made multiparametric MR imaging a feasible and reasonably accurate technique for the local staging of bladder cancer to optimize treatment. In addition, whole-body CT is the primary imaging technique for the detection of metastases in bladder cancer patients, especially those with disease that invades muscle.

Original languageEnglish (US)
Pages (from-to)371-387
Number of pages17
Issue number2
StatePublished - Mar 1 2012

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Verma, S., Rajesh, A., Prasad, S. R., Gaitonde, K., Lall, C. G., Mouraviev, V., Aeron, G., Bracken, R. B., & Sandrasegaran, K. (2012). Urinary bladder cancer: Role of MR imaging. Radiographics, 32(2), 371-387. https://doi.org/10.1148/rg.322115125