US findings of metacarpophalangeal joints in children with idiopathic juvenile arthritis

Boaz Karmazyn, Suzanne L. Bowyer, Kara Murphy Schmidt, Susan H. Ballinger, Kenneth Buckwalter, Thuy T. Beam, Jun Ying

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Background: Juvenile idiopathic arthritis (JIA) is the most common cause of chronic arthritis in children, with frequent involvement of the metacarpophalangeal joints (MCPJ). Objective: To compare US findings with those of radiography and clinical examination. Materials and methods: All MCPJs in 20 children with JIA (17 females, median age 9.7 years, range 3.6 to 16.8 years) were evaluated clinically and imaged with gray-scale and color Doppler US, and 90 MCPJs were also imaged radiographically. Each MCPJ was graded on physical examination from 0 (normal) to 4 (severe) by the patient's rheumatologist. Results: US demonstrated abnormalities in 64 of 200 MCPJs (32.0%), including pannus vascularity and/or tenosynovitis in 55 joints (27.5%) (pannus vascularity in 43, tenosynovitis in 40) and bone destruction in 25 joints (12.5%). Overall, US abnormalities and physical examination scores were significantly associated (P<0.001). However, interobserver agreement between US and clinical evaluation was poor (kappa 0.1) and between US and radiography was only fair (kappa 0.4). Conclusion: US of the MCPJ in children with JIA can demonstrate cartilage thinning, bone erosions, and pannus vascularity. Abnormal US findings are significantly correlated with severity of disease as evaluated clinically.

Original languageEnglish
Pages (from-to)475-482
Number of pages8
JournalPediatric Radiology
Volume37
Issue number5
DOIs
StatePublished - May 2007

Fingerprint

Metacarpophalangeal Joint
Juvenile Arthritis
Tenosynovitis
Radiography
Physical Examination
Joints
Bone and Bones
Arthritis
Cartilage
Color

Keywords

  • Children
  • Idiopathicjuvenile arthritis
  • Metacarpophalangeal joints
  • US

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pediatrics, Perinatology, and Child Health
  • Radiological and Ultrasound Technology

Cite this

Karmazyn, B., Bowyer, S. L., Schmidt, K. M., Ballinger, S. H., Buckwalter, K., Beam, T. T., & Ying, J. (2007). US findings of metacarpophalangeal joints in children with idiopathic juvenile arthritis. Pediatric Radiology, 37(5), 475-482. https://doi.org/10.1007/s00247-007-0438-9

US findings of metacarpophalangeal joints in children with idiopathic juvenile arthritis. / Karmazyn, Boaz; Bowyer, Suzanne L.; Schmidt, Kara Murphy; Ballinger, Susan H.; Buckwalter, Kenneth; Beam, Thuy T.; Ying, Jun.

In: Pediatric Radiology, Vol. 37, No. 5, 05.2007, p. 475-482.

Research output: Contribution to journalArticle

Karmazyn, B, Bowyer, SL, Schmidt, KM, Ballinger, SH, Buckwalter, K, Beam, TT & Ying, J 2007, 'US findings of metacarpophalangeal joints in children with idiopathic juvenile arthritis', Pediatric Radiology, vol. 37, no. 5, pp. 475-482. https://doi.org/10.1007/s00247-007-0438-9
Karmazyn, Boaz ; Bowyer, Suzanne L. ; Schmidt, Kara Murphy ; Ballinger, Susan H. ; Buckwalter, Kenneth ; Beam, Thuy T. ; Ying, Jun. / US findings of metacarpophalangeal joints in children with idiopathic juvenile arthritis. In: Pediatric Radiology. 2007 ; Vol. 37, No. 5. pp. 475-482.
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