Use of an intra-oral model to evaluate 0.05% sodium fluoride mouthrinse in radiation-induced hyposalivation.

C. Meyerowitz, J. D. Featherstone, R. J. Billings, A. D. Eisenberg, J. Fu, M. Shariati, Domenick Zero

Research output: Contribution to journalArticle

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Abstract

The present study was undertaken to evaluate the effect of a twice-daily topical application of a 0.05% NaF mouthrinse on de- and remineralization in the oral cavities of subjects suffering from radiation-induced hyposalivation. Six subjects each wore a bonded intra-oral appliance containing a sound and a demineralized human enamel slab for four weeks. During that period, the subjects used 0.05% NaF rinses, twice daily, instead of the 1.1% NaF gel that had previously been a part of their preventive regimen. Salivary flow rates, plaque pH profiles following a 10% sucrose rinse, S. mutans and lactobacillus counts, fluoride clearance, and enamel microhardness were determined during the study. Sound enamel samples displayed no evidence of demineralization, and the previously demineralized enamel showed remineralization in the outer 50 microns in three of the six subjects. The results suggest that a twice-daily oral rinse with 0.05% NaF can prevent demineralization and enhance remineralization in subjects with radiation-induced hyposalivation.

Original languageEnglish (US)
Pages (from-to)894-898
Number of pages5
JournalJournal of Dental Research
Volume70
Issue number5
StatePublished - May 1991
Externally publishedYes

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Xerostomia
Sodium Fluoride
Dental Enamel
Radiation
Lactobacillus
Fluorides
Sucrose
Mouth
Gels

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Meyerowitz, C., Featherstone, J. D., Billings, R. J., Eisenberg, A. D., Fu, J., Shariati, M., & Zero, D. (1991). Use of an intra-oral model to evaluate 0.05% sodium fluoride mouthrinse in radiation-induced hyposalivation. Journal of Dental Research, 70(5), 894-898.

Use of an intra-oral model to evaluate 0.05% sodium fluoride mouthrinse in radiation-induced hyposalivation. / Meyerowitz, C.; Featherstone, J. D.; Billings, R. J.; Eisenberg, A. D.; Fu, J.; Shariati, M.; Zero, Domenick.

In: Journal of Dental Research, Vol. 70, No. 5, 05.1991, p. 894-898.

Research output: Contribution to journalArticle

Meyerowitz, C, Featherstone, JD, Billings, RJ, Eisenberg, AD, Fu, J, Shariati, M & Zero, D 1991, 'Use of an intra-oral model to evaluate 0.05% sodium fluoride mouthrinse in radiation-induced hyposalivation.', Journal of Dental Research, vol. 70, no. 5, pp. 894-898.
Meyerowitz C, Featherstone JD, Billings RJ, Eisenberg AD, Fu J, Shariati M et al. Use of an intra-oral model to evaluate 0.05% sodium fluoride mouthrinse in radiation-induced hyposalivation. Journal of Dental Research. 1991 May;70(5):894-898.
Meyerowitz, C. ; Featherstone, J. D. ; Billings, R. J. ; Eisenberg, A. D. ; Fu, J. ; Shariati, M. ; Zero, Domenick. / Use of an intra-oral model to evaluate 0.05% sodium fluoride mouthrinse in radiation-induced hyposalivation. In: Journal of Dental Research. 1991 ; Vol. 70, No. 5. pp. 894-898.
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