Use of tanning beds and incidence of skin cancer

Mingfeng Zhang, Abrar A. Qureshi, Alan C. Geller, Lindsay Frazier, David J. Hunter, Jiali Han

Research output: Contribution to journalArticle

129 Citations (Scopus)

Abstract

Purpose: We sought to evaluate the risk effect of tanning bed use on skin cancers among teenage and young adults. We also expected to determine whether a dose-response relationship was evident. Patients and Methods: We observed 73,494 female nurses for 20 years (from 1989 to 2009) in a large and well-characterized cohort in the United States and investigated whether frequency of tanning bed use during high school/college and at ages 25 to 35 years were associated with a risk of basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma. We used Cox proportional hazards models and carefully adjusted for host risk factors, ultraviolet index of residence, and sun exposure behaviors at a young age. Results: During follow-up, 5,506 nurses were diagnosed with BCC, 403 with SCC, and 349 with melanoma. The multivariable-adjusted hazard ratio (HR) of skin cancer for an incremental increase in use of tanning beds of four times per year during both periods was 1.15 (95% CI, 1.11 to 1.19; P < .001) for BCC, 1.15 (95% CI, 1.01 to 1.31; P = .03) for SCC, and 1.11 (95% CI, 0.97 to 1.27; P = .13) for melanoma. Compared with tanning bed use at ages 25 to 35 years, we found a significantly higher risk of BCC for use during high school/college (multivariable-adjusted HR for use more than six times per year compared with no use was 1.73 during high school/college v 1.28 at ages 25 to 35 years; P for heterogeneity < .001). Conclusion: Our data provide evidence for a dose-response relationship between tanning bed use and the risk of skin cancers, especially BCC, and the association is stronger for patients with a younger age at exposure.

Original languageEnglish (US)
Pages (from-to)1588-1593
Number of pages6
JournalJournal of Clinical Oncology
Volume30
Issue number14
DOIs
StatePublished - May 10 2012
Externally publishedYes

Fingerprint

Tanning
Basal Cell Carcinoma
Skin Neoplasms
Incidence
Squamous Cell Carcinoma
Melanoma
Nurses
Solar System
Proportional Hazards Models
Young Adult

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Zhang, M., Qureshi, A. A., Geller, A. C., Frazier, L., Hunter, D. J., & Han, J. (2012). Use of tanning beds and incidence of skin cancer. Journal of Clinical Oncology, 30(14), 1588-1593. https://doi.org/10.1200/JCO.2011.39.3652

Use of tanning beds and incidence of skin cancer. / Zhang, Mingfeng; Qureshi, Abrar A.; Geller, Alan C.; Frazier, Lindsay; Hunter, David J.; Han, Jiali.

In: Journal of Clinical Oncology, Vol. 30, No. 14, 10.05.2012, p. 1588-1593.

Research output: Contribution to journalArticle

Zhang, M, Qureshi, AA, Geller, AC, Frazier, L, Hunter, DJ & Han, J 2012, 'Use of tanning beds and incidence of skin cancer', Journal of Clinical Oncology, vol. 30, no. 14, pp. 1588-1593. https://doi.org/10.1200/JCO.2011.39.3652
Zhang M, Qureshi AA, Geller AC, Frazier L, Hunter DJ, Han J. Use of tanning beds and incidence of skin cancer. Journal of Clinical Oncology. 2012 May 10;30(14):1588-1593. https://doi.org/10.1200/JCO.2011.39.3652
Zhang, Mingfeng ; Qureshi, Abrar A. ; Geller, Alan C. ; Frazier, Lindsay ; Hunter, David J. ; Han, Jiali. / Use of tanning beds and incidence of skin cancer. In: Journal of Clinical Oncology. 2012 ; Vol. 30, No. 14. pp. 1588-1593.
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