Using the agile implementation model to reduce central line–associated bloodstream infections

Jose Azar, Kristen Kelley, Jennifer Dunscomb, Anthony Perkins, Yun Wang, Cole Beeler, Lana Dbeibo, Douglas Webb, Larry Stevens, Mark Luektemeyer, Areeba Kara, Ryan Nagy, Craig A. Solid, Malaz Boustani

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Central line–associated bloodstream infections (CLABSIs) are among the most common hospital-acquired infections and can lead to increased patient morbidity and mortality rates. Implementation of practice guidelines and recommended prevention bundles has historically been suboptimal, suggesting that improvements in implementation methods could further reductions in CLABSI rates. In this article, we describe the agile implementation methodology and present details of how it was successfully used to reduce CLABSI. Methods: We conducted an observational study of patients with central line catheters at 2 adult tertiary care hospitals in Indianapolis from January 2015 to June 2017. Results: The intervention successfully reduced the CLABSI rate from 1.76 infections per 1,000 central line days to 1.24 (rate ratio = 0.70; P =.011). We also observed reductions in the rates of Clostridium difficile and surgical site infections, whereas catheter-associated urinary tract infections remained stable. Conclusions: Using the AI model, we were able to successfully implement evidence-based practices to reduce the rate of CLABSIs at our facility.

Original languageEnglish (US)
JournalAmerican Journal of Infection Control
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Infection
Surgical Wound Infection
Catheter-Related Infections
Clostridium difficile
Evidence-Based Practice
Tertiary Healthcare
Cross Infection
Practice Guidelines
Tertiary Care Centers
Urinary Tract Infections
Observational Studies
Catheters
Morbidity
Mortality

Keywords

  • Central line–associated bloodstream infections
  • Implementation science
  • Quality improvement

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Using the agile implementation model to reduce central line–associated bloodstream infections. / Azar, Jose; Kelley, Kristen; Dunscomb, Jennifer; Perkins, Anthony; Wang, Yun; Beeler, Cole; Dbeibo, Lana; Webb, Douglas; Stevens, Larry; Luektemeyer, Mark; Kara, Areeba; Nagy, Ryan; Solid, Craig A.; Boustani, Malaz.

In: American Journal of Infection Control, 01.01.2018.

Research output: Contribution to journalArticle

Azar, J, Kelley, K, Dunscomb, J, Perkins, A, Wang, Y, Beeler, C, Dbeibo, L, Webb, D, Stevens, L, Luektemeyer, M, Kara, A, Nagy, R, Solid, CA & Boustani, M 2018, 'Using the agile implementation model to reduce central line–associated bloodstream infections', American Journal of Infection Control. https://doi.org/10.1016/j.ajic.2018.07.008
Azar, Jose ; Kelley, Kristen ; Dunscomb, Jennifer ; Perkins, Anthony ; Wang, Yun ; Beeler, Cole ; Dbeibo, Lana ; Webb, Douglas ; Stevens, Larry ; Luektemeyer, Mark ; Kara, Areeba ; Nagy, Ryan ; Solid, Craig A. ; Boustani, Malaz. / Using the agile implementation model to reduce central line–associated bloodstream infections. In: American Journal of Infection Control. 2018.
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