Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS

V. Pirro, A. K. Jarmusch, C. M. Alfaro, E. M. Hattab, Aaron Cohen-Gadol, R. Graham Cooks

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection. DESI-MS allows rapid sampling while providing accurate diagnostic information. We assess the chemical homogeneity of neurological smears using DESI-MS imaging and the quality of rapid DESI-MS diagnosis.

Original languageEnglish (US)
Pages (from-to)449-454
Number of pages6
JournalAnalyst
Volume142
Issue number3
DOIs
StatePublished - Jan 30 2017

Fingerprint

Electrospray ionization
Electrospray Ionization Mass Spectrometry
Brain Neoplasms
tumor
Mass spectrometry
brain
Tumors
cancer
Desorption
Brain
desorption
ionization
mass spectrometry
Cells
homogeneity
Referral and Consultation
Sampling
Imaging techniques
sampling

ASJC Scopus subject areas

  • Analytical Chemistry
  • Environmental Chemistry
  • Biochemistry
  • Spectroscopy
  • Electrochemistry

Cite this

Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS. / Pirro, V.; Jarmusch, A. K.; Alfaro, C. M.; Hattab, E. M.; Cohen-Gadol, Aaron; Cooks, R. Graham.

In: Analyst, Vol. 142, No. 3, 30.01.2017, p. 449-454.

Research output: Contribution to journalArticle

Pirro, V. ; Jarmusch, A. K. ; Alfaro, C. M. ; Hattab, E. M. ; Cohen-Gadol, Aaron ; Cooks, R. Graham. / Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS. In: Analyst. 2017 ; Vol. 142, No. 3. pp. 449-454.
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