Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS

V. Pirro, A. K. Jarmusch, C. M. Alfaro, E. M. Hattab, A. A. Cohen-Gadol, R. Graham Cooks

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection. DESI-MS allows rapid sampling while providing accurate diagnostic information. We assess the chemical homogeneity of neurological smears using DESI-MS imaging and the quality of rapid DESI-MS diagnosis.

Original languageEnglish (US)
Pages (from-to)449-454
Number of pages6
JournalAnalyst
Volume142
Issue number3
DOIs
StatePublished - Jan 30 2017

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

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