Utilization of the Denny-Brown collection: Differential recovery of forelimb and hind limb stepping after extensive unilateral cerebral lesions

Joel A. Vilensky, Sid Gilman, Elizabeth A. Dunn, W. Jeffrey Wilson

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The Denny-Brown collection of primate lesion material was used to test the hypothesis that there is a difference in the rate of forelimb and hind limb recovery of locomotor movements after major unilateral cerebral ablation (pre/postcentral gyrus, decortication or hemispherectomy). The results indicate that, following major cerebral injury, hind limb recovery precedes that of the forelimb in adolescent and adult primates, but not in infants. This suggests that there is an underlying physiological basis to the widely-held belief that, in humans, lower limb recovery after stroke is generally more complete than that of the upper limb.

Original languageEnglish (US)
Pages (from-to)223-233
Number of pages11
JournalBehavioural Brain Research
Volume82
Issue number2
DOIs
StatePublished - Jan 1997

Keywords

  • ablation
  • lesion
  • locomotion
  • primate
  • stroke

ASJC Scopus subject areas

  • Behavioral Neuroscience

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