Vaginal cleansing before cesarean delivery to reduce postoperative infectious morbidity: a randomized, controlled trial

David M. Haas, Fatemeh Pazouki, Ronda R. Smith, Amy M. Fry, Iwona Podzielinski, Sarah M. Al-Darei, Alan M. Golichowski

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Objective: The objective of the study was to determine whether vaginal preparation with povidone iodine before cesarean delivery decreased the risk of postoperative maternal morbidities. Study Design: The design of the study was a randomized, controlled trial in women undergoing cesarean delivery with subjects assigned to have a preoperative vaginal cleansing with povidone iodine or to a standard care group (no vaginal wash). The primary outcome was a composite of postoperative fever, endometritis, sepsis, readmission, wound infection, or complication. Results: There were 155 vaginal cleansing subjects and 145 control subjects. Overall, 9.0% developed the composite outcome, with fewer women in the cleansing group (6.5%) compared with the control group (11.7%), although the difference was not statistically significant (relative risk, 0.55; 95% confidence interval, 0.26-1.11; P = .11). Length of surgery, being in labor, and having a dilated cervix were all associated with the composite morbidity outcome. Conclusion: Vaginal cleansing with povidone iodine before cesarean delivery may decrease postoperative morbidities, although the reduction is not statistically significant.

Original languageEnglish (US)
Pages (from-to)310.e1-310.e6
JournalAmerican Journal of Obstetrics and Gynecology
Volume202
Issue number3
DOIs
StatePublished - Mar 2010

Keywords

  • cesarean delivery
  • postoperative maternal morbidities
  • povidone iodine
  • risk
  • vaginal preparation

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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