Vaginal cleansing before cesarean delivery to reduce postoperative infectious morbidity

a randomized, controlled trial

David Haas, Fatemeh Pazouki, Ronda R. Smith, Amy M. Fry, Iwona Podzielinski, Sarah M. Al-Darei, Alan M. Golichowski

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objective: The objective of the study was to determine whether vaginal preparation with povidone iodine before cesarean delivery decreased the risk of postoperative maternal morbidities. Study Design: The design of the study was a randomized, controlled trial in women undergoing cesarean delivery with subjects assigned to have a preoperative vaginal cleansing with povidone iodine or to a standard care group (no vaginal wash). The primary outcome was a composite of postoperative fever, endometritis, sepsis, readmission, wound infection, or complication. Results: There were 155 vaginal cleansing subjects and 145 control subjects. Overall, 9.0% developed the composite outcome, with fewer women in the cleansing group (6.5%) compared with the control group (11.7%), although the difference was not statistically significant (relative risk, 0.55; 95% confidence interval, 0.26-1.11; P = .11). Length of surgery, being in labor, and having a dilated cervix were all associated with the composite morbidity outcome. Conclusion: Vaginal cleansing with povidone iodine before cesarean delivery may decrease postoperative morbidities, although the reduction is not statistically significant.

Original languageEnglish
JournalAmerican Journal of Obstetrics and Gynecology
Volume202
Issue number3
DOIs
StatePublished - Mar 2010

Fingerprint

Povidone-Iodine
Randomized Controlled Trials
Morbidity
Endometritis
Wound Infection
Cervix Uteri
Sepsis
Fever
Mothers
Confidence Intervals
Control Groups

Keywords

  • cesarean delivery
  • postoperative maternal morbidities
  • povidone iodine
  • risk
  • vaginal preparation

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Vaginal cleansing before cesarean delivery to reduce postoperative infectious morbidity : a randomized, controlled trial. / Haas, David; Pazouki, Fatemeh; Smith, Ronda R.; Fry, Amy M.; Podzielinski, Iwona; Al-Darei, Sarah M.; Golichowski, Alan M.

In: American Journal of Obstetrics and Gynecology, Vol. 202, No. 3, 03.2010.

Research output: Contribution to journalArticle

Haas, David ; Pazouki, Fatemeh ; Smith, Ronda R. ; Fry, Amy M. ; Podzielinski, Iwona ; Al-Darei, Sarah M. ; Golichowski, Alan M. / Vaginal cleansing before cesarean delivery to reduce postoperative infectious morbidity : a randomized, controlled trial. In: American Journal of Obstetrics and Gynecology. 2010 ; Vol. 202, No. 3.
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