Validation of Single-Item Linear Analog Scale Assessment of Quality of Life in Neuro-Oncology Patients

Dona E C Locke, Paul A. Decker, Jeff A. Sloan, Paul D. Brown, James F. Malec, Matthew M. Clark, Teresa A. Rummans, Karla V. Ballman, Paul L. Schaefer, Jan C. Buckner

Research output: Contribution to journalArticle

137 Citations (Scopus)

Abstract

Assessment of patient quality of life (QOL) requires balancing the details provided by multi-item assessments with the reduced burden of single-item assessments. In this project, we investigated the psychometric properties of single-item Linear Analog Scale Assessments (LASAs) for patients with newly diagnosed high-grade gliomas. Measures included QOL LASAs (overall, physical, emotional, spiritual, intellectual), Symptom Distress Scale (SDS), Profile of Mood States (POMS; overall, confusion, fatigue), and Functional Assessment of Cancer Therapy-Brain (FACT-Br; overall, brain, physical, emotional). Associations of LASA measures with SDS, POMS, and FACT-Br domains and with Eastern Cooperative Oncology Group performance score (PS) and Mini-Mental State Examination (MMSE) were assessed. Repeated measures ANOVA models compared the change over time of LASAs and SDS, POMS, and FACT-Br. Two hundred five patients completed the assessments across three time points. To allow comparison across measures, all scores were converted to a scale of 0-100, with higher scores indicating better QOL. LASA mean scores ranged from 60 to 78; SDS, POMS, and FACT-Br ranged from 62 to 81. FACT-Br physical (P <0.001) and POMS fatigue subscale (P = 0.005) decreased over time, as did LASA physical (P = 0.08). LASA scales were strongly associated with corresponding scales on SDS, POMS, and FACT-Br (0.44 <rho <0.65; P <0.001). LASA was negatively associated with PS and positively with MMSE, with associations similar in magnitude to the other QOL and psychosocial measures. The data suggest that the single-item LASA scales are valid for assessing QOL of cancer patients and are an appropriate alternative when a shorter instrument is warranted.

Original languageEnglish (US)
Pages (from-to)628-638
Number of pages11
JournalJournal of Pain and Symptom Management
Volume34
Issue number6
DOIs
StatePublished - Dec 2007
Externally publishedYes

Fingerprint

Quality of Life
Fatigue
Confusion
Symptom Assessment
Psychometrics
Brain Neoplasms
Glioma
Analysis of Variance
Brain
Neoplasms
Therapeutics

Keywords

  • LASA
  • measurement
  • neuro-oncology
  • Quality of life
  • validation

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology
  • Neurology
  • Nursing(all)

Cite this

Locke, D. E. C., Decker, P. A., Sloan, J. A., Brown, P. D., Malec, J. F., Clark, M. M., ... Buckner, J. C. (2007). Validation of Single-Item Linear Analog Scale Assessment of Quality of Life in Neuro-Oncology Patients. Journal of Pain and Symptom Management, 34(6), 628-638. https://doi.org/10.1016/j.jpainsymman.2007.01.016

Validation of Single-Item Linear Analog Scale Assessment of Quality of Life in Neuro-Oncology Patients. / Locke, Dona E C; Decker, Paul A.; Sloan, Jeff A.; Brown, Paul D.; Malec, James F.; Clark, Matthew M.; Rummans, Teresa A.; Ballman, Karla V.; Schaefer, Paul L.; Buckner, Jan C.

In: Journal of Pain and Symptom Management, Vol. 34, No. 6, 12.2007, p. 628-638.

Research output: Contribution to journalArticle

Locke, DEC, Decker, PA, Sloan, JA, Brown, PD, Malec, JF, Clark, MM, Rummans, TA, Ballman, KV, Schaefer, PL & Buckner, JC 2007, 'Validation of Single-Item Linear Analog Scale Assessment of Quality of Life in Neuro-Oncology Patients', Journal of Pain and Symptom Management, vol. 34, no. 6, pp. 628-638. https://doi.org/10.1016/j.jpainsymman.2007.01.016
Locke, Dona E C ; Decker, Paul A. ; Sloan, Jeff A. ; Brown, Paul D. ; Malec, James F. ; Clark, Matthew M. ; Rummans, Teresa A. ; Ballman, Karla V. ; Schaefer, Paul L. ; Buckner, Jan C. / Validation of Single-Item Linear Analog Scale Assessment of Quality of Life in Neuro-Oncology Patients. In: Journal of Pain and Symptom Management. 2007 ; Vol. 34, No. 6. pp. 628-638.
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