Variants of Bladder Cancer

The Pathologist's Point of View[figure parsented]

Antonio Lopez-Beltran, Liang Cheng, Maria R. Raspollini, Rita Canas-Marques, Marina Scarpelli, Alessia Cimadamore, Silvia Gasparrini, Rodolfo Montironi

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Pathologic evaluation of bladder cancer typically reveals great tumor heterogeneity and, therefore, the common observation of urothelial carcinoma exhibiting a wide variety of histopathologic patterns is not surprising. Some of these patterns are so distinctive that they have been recognized as specific variants of urothelial carcinoma. Classifications have recently been revised in the 2016 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs. The current World Health Organization classifications clarify terminological issues and provide better definition criteria, but also incorporates some new entities. Many of these variants have important prognostic or therapeutic implications worth knowing by the urologist and oncologist, but also represent diagnostic challenges in daily practice of pathology. This review will discuss the features of pathologic variants of bladder cancer in the context of our current clinical practice. The features of pathologic variants of bladder cancer in the context of our current clinical practice are discussed.

Original languageEnglish (US)
Pages (from-to)210-222
Number of pages13
JournalEuropean Urology, Supplements
Volume16
Issue number12
DOIs
StatePublished - Dec 1 2017

Fingerprint

Urinary Bladder Neoplasms
Male Genitalia
Carcinoma
Neoplasms
Observation
Pathology
Pathologists
Therapeutics

Keywords

  • Bladder carcinoma
  • Clear cell
  • Giant pleomorphic
  • Glandular
  • Lymphoepithelioma-like
  • Microcystic
  • Micropapillary
  • Nested
  • Plasmacytoid
  • Squamous
  • Variant histology

ASJC Scopus subject areas

  • Urology

Cite this

Lopez-Beltran, A., Cheng, L., Raspollini, M. R., Canas-Marques, R., Scarpelli, M., Cimadamore, A., ... Montironi, R. (2017). Variants of Bladder Cancer: The Pathologist's Point of View[figure parsented]. European Urology, Supplements, 16(12), 210-222. https://doi.org/10.1016/j.eursup.2017.09.004

Variants of Bladder Cancer : The Pathologist's Point of View[figure parsented]. / Lopez-Beltran, Antonio; Cheng, Liang; Raspollini, Maria R.; Canas-Marques, Rita; Scarpelli, Marina; Cimadamore, Alessia; Gasparrini, Silvia; Montironi, Rodolfo.

In: European Urology, Supplements, Vol. 16, No. 12, 01.12.2017, p. 210-222.

Research output: Contribution to journalReview article

Lopez-Beltran, A, Cheng, L, Raspollini, MR, Canas-Marques, R, Scarpelli, M, Cimadamore, A, Gasparrini, S & Montironi, R 2017, 'Variants of Bladder Cancer: The Pathologist's Point of View[figure parsented]', European Urology, Supplements, vol. 16, no. 12, pp. 210-222. https://doi.org/10.1016/j.eursup.2017.09.004
Lopez-Beltran A, Cheng L, Raspollini MR, Canas-Marques R, Scarpelli M, Cimadamore A et al. Variants of Bladder Cancer: The Pathologist's Point of View[figure parsented]. European Urology, Supplements. 2017 Dec 1;16(12):210-222. https://doi.org/10.1016/j.eursup.2017.09.004
Lopez-Beltran, Antonio ; Cheng, Liang ; Raspollini, Maria R. ; Canas-Marques, Rita ; Scarpelli, Marina ; Cimadamore, Alessia ; Gasparrini, Silvia ; Montironi, Rodolfo. / Variants of Bladder Cancer : The Pathologist's Point of View[figure parsented]. In: European Urology, Supplements. 2017 ; Vol. 16, No. 12. pp. 210-222.
@article{3de739a2eeb34dceb64ab1266f157707,
title = "Variants of Bladder Cancer: The Pathologist's Point of View[figure parsented]",
abstract = "Pathologic evaluation of bladder cancer typically reveals great tumor heterogeneity and, therefore, the common observation of urothelial carcinoma exhibiting a wide variety of histopathologic patterns is not surprising. Some of these patterns are so distinctive that they have been recognized as specific variants of urothelial carcinoma. Classifications have recently been revised in the 2016 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs. The current World Health Organization classifications clarify terminological issues and provide better definition criteria, but also incorporates some new entities. Many of these variants have important prognostic or therapeutic implications worth knowing by the urologist and oncologist, but also represent diagnostic challenges in daily practice of pathology. This review will discuss the features of pathologic variants of bladder cancer in the context of our current clinical practice. The features of pathologic variants of bladder cancer in the context of our current clinical practice are discussed.",
keywords = "Bladder carcinoma, Clear cell, Giant pleomorphic, Glandular, Lymphoepithelioma-like, Microcystic, Micropapillary, Nested, Plasmacytoid, Squamous, Variant histology",
author = "Antonio Lopez-Beltran and Liang Cheng and Raspollini, {Maria R.} and Rita Canas-Marques and Marina Scarpelli and Alessia Cimadamore and Silvia Gasparrini and Rodolfo Montironi",
year = "2017",
month = "12",
day = "1",
doi = "10.1016/j.eursup.2017.09.004",
language = "English (US)",
volume = "16",
pages = "210--222",
journal = "European Urology, Supplements",
issn = "1569-9056",
publisher = "Elsevier",
number = "12",

}

TY - JOUR

T1 - Variants of Bladder Cancer

T2 - The Pathologist's Point of View[figure parsented]

AU - Lopez-Beltran, Antonio

AU - Cheng, Liang

AU - Raspollini, Maria R.

AU - Canas-Marques, Rita

AU - Scarpelli, Marina

AU - Cimadamore, Alessia

AU - Gasparrini, Silvia

AU - Montironi, Rodolfo

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Pathologic evaluation of bladder cancer typically reveals great tumor heterogeneity and, therefore, the common observation of urothelial carcinoma exhibiting a wide variety of histopathologic patterns is not surprising. Some of these patterns are so distinctive that they have been recognized as specific variants of urothelial carcinoma. Classifications have recently been revised in the 2016 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs. The current World Health Organization classifications clarify terminological issues and provide better definition criteria, but also incorporates some new entities. Many of these variants have important prognostic or therapeutic implications worth knowing by the urologist and oncologist, but also represent diagnostic challenges in daily practice of pathology. This review will discuss the features of pathologic variants of bladder cancer in the context of our current clinical practice. The features of pathologic variants of bladder cancer in the context of our current clinical practice are discussed.

AB - Pathologic evaluation of bladder cancer typically reveals great tumor heterogeneity and, therefore, the common observation of urothelial carcinoma exhibiting a wide variety of histopathologic patterns is not surprising. Some of these patterns are so distinctive that they have been recognized as specific variants of urothelial carcinoma. Classifications have recently been revised in the 2016 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs. The current World Health Organization classifications clarify terminological issues and provide better definition criteria, but also incorporates some new entities. Many of these variants have important prognostic or therapeutic implications worth knowing by the urologist and oncologist, but also represent diagnostic challenges in daily practice of pathology. This review will discuss the features of pathologic variants of bladder cancer in the context of our current clinical practice. The features of pathologic variants of bladder cancer in the context of our current clinical practice are discussed.

KW - Bladder carcinoma

KW - Clear cell

KW - Giant pleomorphic

KW - Glandular

KW - Lymphoepithelioma-like

KW - Microcystic

KW - Micropapillary

KW - Nested

KW - Plasmacytoid

KW - Squamous

KW - Variant histology

UR - http://www.scopus.com/inward/record.url?scp=85032919561&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032919561&partnerID=8YFLogxK

U2 - 10.1016/j.eursup.2017.09.004

DO - 10.1016/j.eursup.2017.09.004

M3 - Review article

VL - 16

SP - 210

EP - 222

JO - European Urology, Supplements

JF - European Urology, Supplements

SN - 1569-9056

IS - 12

ER -