Variation in Barrett's esophageal wall thickness: Is it associated with histology or segment length?

Kanwar Rupinder S Gill, Marwan Ghabril, Laith H. Jamil, Mohammad Al-Haddad, Seth A. Gross, Sami R. Achem, Timothy A. Woodward, Michael B. Wallace, Massimo Raimondo, Lois L. Hemminger, Herbert C. Wolfsen

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Goals: To measure esophageal wall thickness (EWT) with endoscopic ultrasound (EUS) in patients with and without Barrett's esophagus (BE). Background: Segment length and histology are used to evaluate BE. The development of varying depths of ablation therapy has renewed interest in using EUS for BE. Study: In this prospective study, EWT measurements were taken from the balloon-mucosal interface to the outer most hyper-echoic line. These measurements were correlated with the highest grade of BE dysplasia and segment length, and then compared with the measurements from control group. Results: Between 2004 to 2007, 76 BE patients (69 men, mean age 68 y, 4 ND, 14 low-grade dysplasia, 52 high-grade dysplasia, 6 carcinoma in situ) and 53 normal controls (18 men, mean age 60 y) underwent EUS. The mean EWT was 2.4 mm for controls, 3.1 mm for nondysplastic BE, 3.2 mm for low-grade dysplasia, 3.4 mm for high-grade dysplasia, and 3.9 mm for carcinoma in situ. In the control group of 53 patients, the mean EWT was 2.4 mm. Compared with normal controls, the mean EWT was significantly greater in all histologic subgroups of BE patients (P

Original languageEnglish (US)
Pages (from-to)411-415
Number of pages5
JournalJournal of Clinical Gastroenterology
Volume44
Issue number6
DOIs
StatePublished - Jul 2010
Externally publishedYes

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Barrett Esophagus
Histology
Carcinoma in Situ
Control Groups
Prospective Studies

Keywords

  • Barrett's esophagus
  • dysplasia
  • endoscopic ultrasound
  • esophageal wall thickness

ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

Cite this

Variation in Barrett's esophageal wall thickness : Is it associated with histology or segment length? / Gill, Kanwar Rupinder S; Ghabril, Marwan; Jamil, Laith H.; Al-Haddad, Mohammad; Gross, Seth A.; Achem, Sami R.; Woodward, Timothy A.; Wallace, Michael B.; Raimondo, Massimo; Hemminger, Lois L.; Wolfsen, Herbert C.

In: Journal of Clinical Gastroenterology, Vol. 44, No. 6, 07.2010, p. 411-415.

Research output: Contribution to journalArticle

Gill, KRS, Ghabril, M, Jamil, LH, Al-Haddad, M, Gross, SA, Achem, SR, Woodward, TA, Wallace, MB, Raimondo, M, Hemminger, LL & Wolfsen, HC 2010, 'Variation in Barrett's esophageal wall thickness: Is it associated with histology or segment length?', Journal of Clinical Gastroenterology, vol. 44, no. 6, pp. 411-415. https://doi.org/10.1097/MCG.0b013e3181dd8cd7
Gill, Kanwar Rupinder S ; Ghabril, Marwan ; Jamil, Laith H. ; Al-Haddad, Mohammad ; Gross, Seth A. ; Achem, Sami R. ; Woodward, Timothy A. ; Wallace, Michael B. ; Raimondo, Massimo ; Hemminger, Lois L. ; Wolfsen, Herbert C. / Variation in Barrett's esophageal wall thickness : Is it associated with histology or segment length?. In: Journal of Clinical Gastroenterology. 2010 ; Vol. 44, No. 6. pp. 411-415.
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