Vascular considerations in postchemotherapy - Retroperitoneal lymph-node dissection

part I - Vena cava

J. P. Donohue, J. A. Thornhill, Richard Foster, Richard Bihrle

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A total of 42 patients underwent inferior vena cava resection (n=40) or intraluminal tumor thrombectomy (n=2) during retroperitoneal lymph-node dissection (RPLND) for bulky abdominal metastatic nonseminomatous germ-cell cancer (7% of all postchemotherapy RPLND cases). The three indications for caval resection included tumor clearance (38%), caval scar occlusion (14%), and caval tumor thrombus (48%). En bloc caval resection to achieve tumor clearance was justified by subsequent nodal pathology (cancer in 63% of specimens, teratoma in 31% specimens). Caval resection in the presence of scar occlusion was required de facto by virtue of its incorporation in the specimen. Caval resection or thrombectomy is indicated for intraluminal tumor thrombus because thrombus pathology (cancer, 35%; teratoma, 45%; fibrosis, 20%) reflected nodal pathology in 71% of cancer cases, 78% of teratoma cases, and 100% of fibrosis cases. The complications of caval resection were generally transitory. The 71% survival rate justifies this intensive surgical approach because these patients had exhausted all chemotherapeutic options.

Original languageEnglish
Pages (from-to)182-186
Number of pages5
JournalWorld Journal of Urology
Volume12
Issue number4
DOIs
StatePublished - Aug 1994

Fingerprint

Venae Cavae
Lymph Node Excision
Blood Vessels
Neoplasms
Teratoma
Thrombectomy
Thrombosis
Pathology
Cicatrix
Fibrosis
Germ Cell and Embryonal Neoplasms
Inferior Vena Cava
Survival Rate

ASJC Scopus subject areas

  • Urology

Cite this

Vascular considerations in postchemotherapy - Retroperitoneal lymph-node dissection : part I - Vena cava. / Donohue, J. P.; Thornhill, J. A.; Foster, Richard; Bihrle, Richard.

In: World Journal of Urology, Vol. 12, No. 4, 08.1994, p. 182-186.

Research output: Contribution to journalArticle

@article{f355aebd26ad4133bb37cb5862876b3a,
title = "Vascular considerations in postchemotherapy - Retroperitoneal lymph-node dissection: part I - Vena cava",
abstract = "A total of 42 patients underwent inferior vena cava resection (n=40) or intraluminal tumor thrombectomy (n=2) during retroperitoneal lymph-node dissection (RPLND) for bulky abdominal metastatic nonseminomatous germ-cell cancer (7{\%} of all postchemotherapy RPLND cases). The three indications for caval resection included tumor clearance (38{\%}), caval scar occlusion (14{\%}), and caval tumor thrombus (48{\%}). En bloc caval resection to achieve tumor clearance was justified by subsequent nodal pathology (cancer in 63{\%} of specimens, teratoma in 31{\%} specimens). Caval resection in the presence of scar occlusion was required de facto by virtue of its incorporation in the specimen. Caval resection or thrombectomy is indicated for intraluminal tumor thrombus because thrombus pathology (cancer, 35{\%}; teratoma, 45{\%}; fibrosis, 20{\%}) reflected nodal pathology in 71{\%} of cancer cases, 78{\%} of teratoma cases, and 100{\%} of fibrosis cases. The complications of caval resection were generally transitory. The 71{\%} survival rate justifies this intensive surgical approach because these patients had exhausted all chemotherapeutic options.",
author = "Donohue, {J. P.} and Thornhill, {J. A.} and Richard Foster and Richard Bihrle",
year = "1994",
month = "8",
doi = "10.1007/BF00185668",
language = "English",
volume = "12",
pages = "182--186",
journal = "World Journal of Urology",
issn = "0724-4983",
publisher = "Springer Verlag",
number = "4",

}

TY - JOUR

T1 - Vascular considerations in postchemotherapy - Retroperitoneal lymph-node dissection

T2 - part I - Vena cava

AU - Donohue, J. P.

AU - Thornhill, J. A.

AU - Foster, Richard

AU - Bihrle, Richard

PY - 1994/8

Y1 - 1994/8

N2 - A total of 42 patients underwent inferior vena cava resection (n=40) or intraluminal tumor thrombectomy (n=2) during retroperitoneal lymph-node dissection (RPLND) for bulky abdominal metastatic nonseminomatous germ-cell cancer (7% of all postchemotherapy RPLND cases). The three indications for caval resection included tumor clearance (38%), caval scar occlusion (14%), and caval tumor thrombus (48%). En bloc caval resection to achieve tumor clearance was justified by subsequent nodal pathology (cancer in 63% of specimens, teratoma in 31% specimens). Caval resection in the presence of scar occlusion was required de facto by virtue of its incorporation in the specimen. Caval resection or thrombectomy is indicated for intraluminal tumor thrombus because thrombus pathology (cancer, 35%; teratoma, 45%; fibrosis, 20%) reflected nodal pathology in 71% of cancer cases, 78% of teratoma cases, and 100% of fibrosis cases. The complications of caval resection were generally transitory. The 71% survival rate justifies this intensive surgical approach because these patients had exhausted all chemotherapeutic options.

AB - A total of 42 patients underwent inferior vena cava resection (n=40) or intraluminal tumor thrombectomy (n=2) during retroperitoneal lymph-node dissection (RPLND) for bulky abdominal metastatic nonseminomatous germ-cell cancer (7% of all postchemotherapy RPLND cases). The three indications for caval resection included tumor clearance (38%), caval scar occlusion (14%), and caval tumor thrombus (48%). En bloc caval resection to achieve tumor clearance was justified by subsequent nodal pathology (cancer in 63% of specimens, teratoma in 31% specimens). Caval resection in the presence of scar occlusion was required de facto by virtue of its incorporation in the specimen. Caval resection or thrombectomy is indicated for intraluminal tumor thrombus because thrombus pathology (cancer, 35%; teratoma, 45%; fibrosis, 20%) reflected nodal pathology in 71% of cancer cases, 78% of teratoma cases, and 100% of fibrosis cases. The complications of caval resection were generally transitory. The 71% survival rate justifies this intensive surgical approach because these patients had exhausted all chemotherapeutic options.

UR - http://www.scopus.com/inward/record.url?scp=0028723939&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028723939&partnerID=8YFLogxK

U2 - 10.1007/BF00185668

DO - 10.1007/BF00185668

M3 - Article

VL - 12

SP - 182

EP - 186

JO - World Journal of Urology

JF - World Journal of Urology

SN - 0724-4983

IS - 4

ER -