Vasodilator Therapies in the Treatment of Acute Heart Failure

Daniel B. Holt, Peter S. Pang

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Purpose of Review: Vasodilators are commonly recommended to treat acute heart failure (AHF), yet they are infrequently used. This review aims to evaluate the clinical utility of traditional, historical, and novel vasodilators in the treatment of AHF. Recent Findings: No traditional vasodilator (i.e., nitroglycerin) therapy definitely improves short- or long-term outcomes. Despite repeated efforts to develop new pharmacologic treatments, no novel therapy outperforms traditional management. At the present time, we continue to recommend traditional vasodilators, such as nitroglycerin. Summary: The use of select vasodilators in the treatment of AHF improves hemodynamics and provides short-term relief; however, data regarding long-term benefits is lacking.

Original languageEnglish (US)
Pages (from-to)32-37
Number of pages6
JournalCurrent Heart Failure Reports
Issue number1
StatePublished - Feb 15 2019


  • Acute heart failure
  • Vasodilator(s)

ASJC Scopus subject areas

  • Emergency Medicine
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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