Ventilation and oxygenation changes during sleep in cystic fibrosis

Robert Tepper, J. B. Skatrud, J. A. Dempsey

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Oxygen desaturation during sleep in patients with cystic fibrosis has been attributed to changes in the end-expiratory volume during rapid eye movement (REM) sleep, leading to worsening of the ventilation-perfusion distribution. The purpose of this study was to describe the changes in ventilation during sleep that may contribute to the oxygen desaturation. Six adolescent males with moderate to severe cystic fibrosis were studied. It was concluded that hypoventilation during REM may contribute to oxygen desaturation in patients with cystic fibrosis.

Original languageEnglish
Pages (from-to)388-393
Number of pages6
JournalChest
Volume84
Issue number4
StatePublished - 1983
Externally publishedYes

Fingerprint

Cystic Fibrosis
Ventilation
Sleep
REM Sleep
Oxygen
Hypoventilation
Perfusion

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Tepper, R., Skatrud, J. B., & Dempsey, J. A. (1983). Ventilation and oxygenation changes during sleep in cystic fibrosis. Chest, 84(4), 388-393.

Ventilation and oxygenation changes during sleep in cystic fibrosis. / Tepper, Robert; Skatrud, J. B.; Dempsey, J. A.

In: Chest, Vol. 84, No. 4, 1983, p. 388-393.

Research output: Contribution to journalArticle

Tepper, R, Skatrud, JB & Dempsey, JA 1983, 'Ventilation and oxygenation changes during sleep in cystic fibrosis', Chest, vol. 84, no. 4, pp. 388-393.
Tepper, Robert ; Skatrud, J. B. ; Dempsey, J. A. / Ventilation and oxygenation changes during sleep in cystic fibrosis. In: Chest. 1983 ; Vol. 84, No. 4. pp. 388-393.
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