Villous adenoma of the uterine cervix associated with invasive adenocarcinoma: A histologic, ultrastructural, and immunohistochemical study

Helen Michael, Gregory Sutton, Meredith T. Hull, Lawrence M. Roth

Research output: Contribution to journalArticle

28 Scopus citations


An unusual neoplasm of the uterine cervix had the features of a villous adenoma with an adjacent adenocarcinoma. Histologic and electron microscopic features of the lesion are described, as well as immunohistochemical staining of the lesion for carcinoembryonic antigen. Electron microscopic evidence of intestinal differentiation in the villous adenoma suggests a rarely recognized potential for intestinal metaplasia in the uterine cervix. The association of villous adenoma with cervical adenocarcinoma underscores the malignant potential and the need for complete excision of this rare cervical lesion.

Original languageEnglish (US)
Pages (from-to)163-169
Number of pages7
JournalInternational Journal of Gynecological Pathology
Issue number2
StatePublished - Jun 1986



  • Adenocarcinoma
  • Cervix
  • Villous adenoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

Cite this