Vitamin D status and calcium metabolism in adolescent black and white girls on a range of controlled calcium intakes

Connie M. Weaver, Linda D. McCabe, George P. McCabe, Michelle Braun, Berdine R. Martin, Linda DiMeglio, Munro Peacock

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Background: There are limited data in adolescents on racial differences in relationships between dietary calcium intake, absorption, and retention and serum levels of calcium-regulating hormones. Objectives: The aim of this study was to investigate these relationships cross-sectionally in American White and Black adolescent girls. Methods: Calcium balance studies were conducted in 105 girls, aged 11-15 yr, on daily calcium intakes ranging from 760-2195 mg for 3-wk controlled feeding periods; 158 observations from 52 Black and 53 White girls were analyzed. Results: Black girls had lower serum 25-hydroxyvitamin D [25(OH)D], higher serum 1,25-dihydroxyvitamin D, and higher calcium absorption and retention than White girls. Calcium intake and race, but not serum 25(OH)D, predicted net calcium absorption and retention with Black girls absorbing calcium more efficiently at low calcium intakes than White girls. The relationship between serum 25(OH)D and serum PTH was negative only in White girls. Calcium intake, race, and postmenarcheal age explained 21% of the variation in calcium retention, and serum 25(OH)D did not contribute further to the variance. Conclusions: These results suggest that serum 25(OH)D does not contribute to the racial differences in calcium absorption and retention during puberty.

Original languageEnglish
Pages (from-to)3907-3914
Number of pages8
JournalJournal of Clinical Endocrinology and Metabolism
Volume93
Issue number10
DOIs
StatePublished - Oct 2008

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Metabolism
Vitamin D
Calcium
Serum
hydroquinone
Dietary Calcium
Puberty
Hormones

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Endocrinology
  • Biochemistry, medical
  • Endocrinology, Diabetes and Metabolism

Cite this

Vitamin D status and calcium metabolism in adolescent black and white girls on a range of controlled calcium intakes. / Weaver, Connie M.; McCabe, Linda D.; McCabe, George P.; Braun, Michelle; Martin, Berdine R.; DiMeglio, Linda; Peacock, Munro.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 10, 10.2008, p. 3907-3914.

Research output: Contribution to journalArticle

Weaver, Connie M. ; McCabe, Linda D. ; McCabe, George P. ; Braun, Michelle ; Martin, Berdine R. ; DiMeglio, Linda ; Peacock, Munro. / Vitamin D status and calcium metabolism in adolescent black and white girls on a range of controlled calcium intakes. In: Journal of Clinical Endocrinology and Metabolism. 2008 ; Vol. 93, No. 10. pp. 3907-3914.
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