von Hippel-Lindau Disease: Epididymal Cystadenoma Targeted by Metastatic Events

Gautam U. Mehta, Sharon B. Shively, Sven Gläsker, Charles J. Bechert, Zhengping Zhuang, Mark Raffeld, Russell R. Lonser, Edward H. Oldfield, Alexander O. Vortmeyer

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Cases of renal clear cell carcinoma in patients with von Hippel-Lindau disease often exhibit extensive metastasis. Several investigators have shown these tumors to specifically invade central nervous system hemangioblastomas, which are commonly associated with the disease. We report on multiple metastatic events within a single von Hippel-Lindau disease-associated tumor outside the central nervous system, epididymal cystadenoma. The multiplicity of these metastatic events suggests the epididymal cystadenoma as a preferential site of metastasis for von Hippel-Lindau disease-associated renal clear cell carcinoma.

Original languageEnglish (US)
Pages (from-to)1209.e9-1209.e12
Issue number6
StatePublished - Jun 2007
Externally publishedYes

ASJC Scopus subject areas

  • Urology

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