Where Are We Headed with Neuromodulation for Overactive Bladder?

Kaitlin Jaqua, Charles Powell

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Overactive bladder (OAB) affects millions of people around the world and decreases quality of life for those affected. Over the past two decades, significant advances in treatment have transformed the lives of those with OAB. Sacral neuromodulation (SNM), posterior tibial nerve stimulation (PTNS), and dorsal genital nerve stimulation are the most effective contemporary treatment modalities. New techniques and bio-sensing schemes offer promise to advance therapy beyond what is currently available. Current neuromodulation techniques do not use real-time data from the body or input from the patient. Incorporating this is the goal of those pursuing a neuroprosthesis to enhance bladder function for these patients. Dorsal genital nerve, pudendal nerve, S3 afferent nerve roots, and S1 and S2 ganglia have all been used as targets for stimulation. Some of these have also been used as sources of afferent nerve information to detect significant bladder events and even to estimate the fullness of the bladder. As technology improves, an intelligent neuroprosthesis with the ability to sense significant bladder events may revolutionize treatment of OAB.

Original languageEnglish (US)
Article number59
JournalCurrent Urology Reports
Volume18
Issue number8
DOIs
StatePublished - Aug 1 2017

Keywords

  • Overactive bladder
  • Posterior tibial nerve stimulation
  • Sacral neuromodulation
  • Voiding dysfunction

ASJC Scopus subject areas

  • Urology

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