Women at risk for gonorrhea: Comparison of rosaramicin and ampicillin plus probenecid in the eradication of neisseria gonorrhoeae, chlamydia trachomatis and genital mycoplasmas

Byron Batteiger, Beth E Walters Zwickl, Morris L V French, Robert B. Jones

Research output: Contribution to journalArticle

Abstract

Rosaramicin is a macrolide antibiotic with activity against Neisseria gonorrhoeae, Chlamydia trachomatis, and the genital mycoplasmas Ureaplasma urealyticum and Mycoplasma hom­inis. Its efficacy in the treatment of genital infections was evaluated and compared with that of single-dose ampicillin plus probenicid in women with known, or suspected, uncom­plicated gonococcal infection. Isolation rates for N. gonorrhoeae, C. trachomatis, U. urealyticum, and M. hominis were 72%, 44%, 95%, and 65%, respectively. Rosaramicin cured 24 (89%) of 27 gonococcal infections and 11 (92%) of 12 chlamydial infections. It transiently reduced the carriage of U. urealyticum but had little effect on carriage of M. hominis. Rosaramicin may be of value in the treatment of concurrent gonococcal and chlamydial infections when tetracycline is contraindicated.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalSexually Transmitted Diseases
Volume12
Issue number1
StatePublished - 1985

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Probenecid
Neisseria gonorrhoeae
Mycoplasma
Gonorrhea
Chlamydia trachomatis
Ampicillin
Mycoplasma hominis
Ureaplasma urealyticum
Infection
Macrolides
Tetracycline
rosaramicin
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases
  • Microbiology (medical)
  • Public Health, Environmental and Occupational Health

Cite this

Women at risk for gonorrhea : Comparison of rosaramicin and ampicillin plus probenecid in the eradication of neisseria gonorrhoeae, chlamydia trachomatis and genital mycoplasmas. / Batteiger, Byron; Zwickl, Beth E Walters; French, Morris L V; Jones, Robert B.

In: Sexually Transmitted Diseases, Vol. 12, No. 1, 1985, p. 1-4.

Research output: Contribution to journalArticle

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