Abstract
Background/Purpose: There is little published data on the efficacy of surgical infection prophylaxis in children. The purpose of this study was to assess wound infection rate in children undergoing colostomy closure for imperforate anus and evaluate the impact of bowel preparation and antibiotics. Methods: Children younger than 18 years with imperforate anus who had a colostomy closure between January 1996 and December 2007 were identified. Data collected included demographics, bowel preparation, antibiotics, operative details, and postoperative infections. Comparison of mechanical bowel preparation and intravenous antibiotics with and without oral antibiotics was compared using χ2 tests. Significance was defined as P < .05. Results: A total of 118 patients were identified. Primary skin closure was done in 97%. Mechanical bowel preparation was used in 93%, intravenous antibiotics in 97%, and oral preoperative antibiotics in 52%. Wound infections occurred in 14% (n = 17). The addition of oral antibiotics to the standard regimen of mechanical bowel preparation with intravenous antibiotics did not alter infection rate (13% versus 17%, P = .64). Conclusion: Wound infection in children undergoing elective colostomy closure for imperforate anus was 14%. Infection rate was not affected by use of oral antibiotics. Future studies may allow specific guideline development for infection prophylaxis in pediatric patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1509-1513 |
| Number of pages | 5 |
| Journal | Journal of pediatric surgery |
| Volume | 45 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2010 |
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Keywords
- Bowel preparation
- Colostomy closure
- Wound infection
ASJC Scopus subject areas
- Surgery
- Pediatrics, Perinatology, and Child Health
- Medicine(all)
Cite this
Wound infection after colostomy closure for imperforate anus in children : Utility of preoperative oral antibiotics. / Breckler, Francine D.; Rescorla, Frederick J.; Billmire, Deborah F.
In: Journal of pediatric surgery, Vol. 45, No. 7, 07.2010, p. 1509-1513.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Wound infection after colostomy closure for imperforate anus in children
T2 - Utility of preoperative oral antibiotics
AU - Breckler, Francine D.
AU - Rescorla, Frederick J.
AU - Billmire, Deborah F.
PY - 2010/7
Y1 - 2010/7
N2 - Background/Purpose: There is little published data on the efficacy of surgical infection prophylaxis in children. The purpose of this study was to assess wound infection rate in children undergoing colostomy closure for imperforate anus and evaluate the impact of bowel preparation and antibiotics. Methods: Children younger than 18 years with imperforate anus who had a colostomy closure between January 1996 and December 2007 were identified. Data collected included demographics, bowel preparation, antibiotics, operative details, and postoperative infections. Comparison of mechanical bowel preparation and intravenous antibiotics with and without oral antibiotics was compared using χ2 tests. Significance was defined as P < .05. Results: A total of 118 patients were identified. Primary skin closure was done in 97%. Mechanical bowel preparation was used in 93%, intravenous antibiotics in 97%, and oral preoperative antibiotics in 52%. Wound infections occurred in 14% (n = 17). The addition of oral antibiotics to the standard regimen of mechanical bowel preparation with intravenous antibiotics did not alter infection rate (13% versus 17%, P = .64). Conclusion: Wound infection in children undergoing elective colostomy closure for imperforate anus was 14%. Infection rate was not affected by use of oral antibiotics. Future studies may allow specific guideline development for infection prophylaxis in pediatric patients.
AB - Background/Purpose: There is little published data on the efficacy of surgical infection prophylaxis in children. The purpose of this study was to assess wound infection rate in children undergoing colostomy closure for imperforate anus and evaluate the impact of bowel preparation and antibiotics. Methods: Children younger than 18 years with imperforate anus who had a colostomy closure between January 1996 and December 2007 were identified. Data collected included demographics, bowel preparation, antibiotics, operative details, and postoperative infections. Comparison of mechanical bowel preparation and intravenous antibiotics with and without oral antibiotics was compared using χ2 tests. Significance was defined as P < .05. Results: A total of 118 patients were identified. Primary skin closure was done in 97%. Mechanical bowel preparation was used in 93%, intravenous antibiotics in 97%, and oral preoperative antibiotics in 52%. Wound infections occurred in 14% (n = 17). The addition of oral antibiotics to the standard regimen of mechanical bowel preparation with intravenous antibiotics did not alter infection rate (13% versus 17%, P = .64). Conclusion: Wound infection in children undergoing elective colostomy closure for imperforate anus was 14%. Infection rate was not affected by use of oral antibiotics. Future studies may allow specific guideline development for infection prophylaxis in pediatric patients.
KW - Bowel preparation
KW - Colostomy closure
KW - Wound infection
UR - http://www.scopus.com/inward/record.url?scp=77955639062&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77955639062&partnerID=8YFLogxK
U2 - 10.1016/j.jpedsurg.2009.10.054
DO - 10.1016/j.jpedsurg.2009.10.054
M3 - Article
C2 - 20638534
AN - SCOPUS:77955639062
VL - 45
SP - 1509
EP - 1513
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
SN - 0022-3468
IS - 7
ER -