X-ray crystallography and the elucidation of the structure of DNA

Hugh C.J. McGregor, Richard B. Gunderman

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

OBJECTIVE. Since their discovery by Roentgen in 1895, x-rays have contributed to some of the most important advances in science. X-ray crystallography is an imaging technique that uses x-ray diffraction to evaluate the molecular structure of a crystalline solid. This article discusses the critical role played by x-ray crystallography in the elucidation of the structure of DNA. CONCLUSION. The story of DNA includes insights on molecular structure provided by x-rays and also lessons on scientific collaboration and innovation that can be applied to radiology today.

Original languageEnglish (US)
Pages (from-to)W689-W692
JournalAmerican Journal of Roentgenology
Volume196
Issue number6
DOIs
StatePublished - Jun 1 2011

Keywords

  • Genetics
  • History
  • Radiology
  • X-ray crystallography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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