X-ray CT high-density artefact suppression in cryosurgery

Jikun Wei, George A. Sandison, Laigao Chen, Yun Liang, Lisa X. Xu

Research output: Contribution to journalReview article

17 Citations (Scopus)

Abstract

Advantages of x-ray CT for imaging guidance of cryosurgery include 3D visualization of frozen and unfrozen tissue and calibration of temperature in the tissue water-ice interface (0-10 °C) to Hounsfield units. However, use of x-ray CT images and their thermal calibration can be compromised by the cryoprobes generating high-density streak artefacts. A new subtraction technique for artefact suppression is proposed and tested in prostate cryosurgery simulations. By subtracting the measured CT x-ray projection profile without cryoprobes from the profile with cryoprobes plus iceballs, one obtains the combined profile of the cryoprobes and a low value background. Polynomial interpolation to obtain the background profile allows its addition to the original profile without probes. The result may then be fed to a conventional filtered back-projection routine to reconstruct the probe-free image. Finally the cryoprobe pixels in the originally constructed image with probes and iceballs are added back to the probe-free image to get the final artefact-suppressed image. The major advantage of this subtraction technique is that it can successfully suppress the high-density artefacts in bone-abundant body regions such as the pelvis. X-ray CT images of cryoprobe arrays in a homogeneous gelatin phantom and the pelvic region of an anthropomorphic Rando phantom containing a human skeleton were generated. After suppression, cryoprobe metal artefact streaks are reduced and visualization of the positions and dimensions of the cryoprobes are well preserved.

Original languageEnglish (US)
Pages (from-to)N319-N326
JournalPhysics in Medicine and Biology
Volume47
Issue number24
DOIs
StatePublished - Dec 21 2002

Fingerprint

Cryosurgery
X Ray Computed Tomography
Artifacts
artifacts
retarding
X rays
Subtraction Technique
X-Rays
profiles
Pelvis
x rays
Visualization
probes
Calibration
Tissue
subtraction
projection
Body Regions
Ice
Gelatin

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

X-ray CT high-density artefact suppression in cryosurgery. / Wei, Jikun; Sandison, George A.; Chen, Laigao; Liang, Yun; Xu, Lisa X.

In: Physics in Medicine and Biology, Vol. 47, No. 24, 21.12.2002, p. N319-N326.

Research output: Contribution to journalReview article

Wei, Jikun ; Sandison, George A. ; Chen, Laigao ; Liang, Yun ; Xu, Lisa X. / X-ray CT high-density artefact suppression in cryosurgery. In: Physics in Medicine and Biology. 2002 ; Vol. 47, No. 24. pp. N319-N326.
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