Youth-onset type 2 diabetes consensus report: Current status, challenges, and priorities

Kristen J. Nadeau, Barbara J. Anderson, Erika G. Berg, Jane L. Chiang, Hubert Chou, Kenneth C. Copeland, Tamara Hannon, Terry T K Huang, Jane L. Lynch, Jeff Powell, Elizabeth Sellers, William V. Tamborlane, Philip Zeitler

Research output: Contribution to journalArticle

100 Scopus citations

Abstract

Type 2 diabetes is a significant and increasing burden in adolescents and young adults. Clear strategies for research, prevention, and treatment of the disease in these vulnerable patients are needed. Evidence suggests that type 2 diabetes in children is different not only from type 1 but also from type 2 diabetes in adults. Understanding the unique pathophysiology of type 2 diabetes in youth, as well as the risk of complications and the psychosocial impact, will enable industry, academia, funding agencies, advocacy groups, and regulators to collectively evaluate both current and future research, treatment, and prevention approaches. This Consensus Report characterizes type 2 diabetes in children, evaluates the fundamental differences between childhood and adult disease, describes the current therapeutic options, and discusses challenges to and approaches for developing new treatments.

Original languageEnglish (US)
Pages (from-to)1635-1642
Number of pages8
JournalDiabetes Care
Volume39
Issue number9
DOIs
StatePublished - Sep 1 2016

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

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    Nadeau, K. J., Anderson, B. J., Berg, E. G., Chiang, J. L., Chou, H., Copeland, K. C., Hannon, T., Huang, T. T. K., Lynch, J. L., Powell, J., Sellers, E., Tamborlane, W. V., & Zeitler, P. (2016). Youth-onset type 2 diabetes consensus report: Current status, challenges, and priorities. Diabetes Care, 39(9), 1635-1642. https://doi.org/10.2337/dc16-1066