Abstract
The ongoing epidemic of Zika fever in the Western Hemisphere has drawn considerable attention from the medical and scientific communities as well as the general public, largely because of its association with birth defects and postinfectious sequelae. Since its appearance in Brazil in 2015, Zika virus has spread to more than 45 countries in the Western Hemisphere and has caused countless infections. To date, no treatment or vaccine exists, but a considerable multinational effort to halt Zika virus transmission is underway. This article reviews the basic biology, epidemiology, pathophysiology, diagnosis, and treatment of Zika virus and Zika fever.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 253-267 |
| Number of pages | 15 |
| Journal | Clinics in Laboratory Medicine |
| Volume | 37 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 1 2017 |
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Keywords
- Arbovirus
- Autochthonous
- Birth defects
- Flaviviridae
- Flavivirus
- Guillain-Barré syndrome
- Microcephaply
ASJC Scopus subject areas
- Clinical Biochemistry
- Biochemistry, medical
Cite this
Zika Virus. / Relich, Ryan; Loeffelholz, Michael.
In: Clinics in Laboratory Medicine, Vol. 37, No. 2, 01.06.2017, p. 253-267.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Zika Virus
AU - Relich, Ryan
AU - Loeffelholz, Michael
PY - 2017/6/1
Y1 - 2017/6/1
N2 - The ongoing epidemic of Zika fever in the Western Hemisphere has drawn considerable attention from the medical and scientific communities as well as the general public, largely because of its association with birth defects and postinfectious sequelae. Since its appearance in Brazil in 2015, Zika virus has spread to more than 45 countries in the Western Hemisphere and has caused countless infections. To date, no treatment or vaccine exists, but a considerable multinational effort to halt Zika virus transmission is underway. This article reviews the basic biology, epidemiology, pathophysiology, diagnosis, and treatment of Zika virus and Zika fever.
AB - The ongoing epidemic of Zika fever in the Western Hemisphere has drawn considerable attention from the medical and scientific communities as well as the general public, largely because of its association with birth defects and postinfectious sequelae. Since its appearance in Brazil in 2015, Zika virus has spread to more than 45 countries in the Western Hemisphere and has caused countless infections. To date, no treatment or vaccine exists, but a considerable multinational effort to halt Zika virus transmission is underway. This article reviews the basic biology, epidemiology, pathophysiology, diagnosis, and treatment of Zika virus and Zika fever.
KW - Arbovirus
KW - Autochthonous
KW - Birth defects
KW - Flaviviridae
KW - Flavivirus
KW - Guillain-Barré syndrome
KW - Microcephaply
UR - http://www.scopus.com/inward/record.url?scp=85016464546&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85016464546&partnerID=8YFLogxK
U2 - 10.1016/j.cll.2017.01.002
DO - 10.1016/j.cll.2017.01.002
M3 - Review article
C2 - 28457349
AN - SCOPUS:85016464546
VL - 37
SP - 253
EP - 267
JO - Clinics in Laboratory Medicine
JF - Clinics in Laboratory Medicine
SN - 0272-2712
IS - 2
ER -